Evidence map›Paper›PMID 32399105›Full record

ArticleArchives of medical science : AMS2020

The telomere length of gastric mucosal samples and peripheral blood lymphocytes in patients who have undergone Billroth II distal gastrectomy.

Muge Ustaoglu, Ahmet Bektas, Abdulkerim Bedir, Tulay Bakir, Aynur Duzgun, Rukiye Nar, Ozgur Ecemis, Rahmi Aslan

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muge UstaogluDepartment of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Ahmet BektasDepartment of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Abdulkerim BedirDepartment of Medical Biochemistry, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Tulay BakirDepartment of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Aynur DuzgunDepartment of Medical Biochemistry, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Rukiye NarDepartment of Medical Biochemistry, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Ozgur EcemisDepartment of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Rahmi AslanDepartment of Gastroenterology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTelomeres play an important role in maintaining chromosomal integrity. Functional loss of telomeres increases the risk of cancer by causing genomic instability. Telomere length abnormalities have been reported in several precancerous lesions. There is no study that evaluates telomere length in Billroth II distal gastrectomy, which is known as a risk factor for gastric stump carcinogenesis, in the literature. The aim of this study was to assess the relationship between the telomere length of residual gastric mucosal samples, peripheral blood lymphocytes, and other clinicopathological parameters of patients who had undergone Billroth II distal gastrectomy. MATERIAL AND

methodsThere were two groups: a control group (

resultsIt was observed that the lengths of the telomeres were shortened as the time of postoperative period increased in the patient group (

conclusionsThe telomere length was shortened as the time of postoperative period increased in the patient group. The telomeres were also shorter in chronic inflammation, neutrophil activity, intestinal metaplasia, and glandular atrophy, in all of the study groups. Telomere length abnormalities in gastric stump carcinogenesis process may be a guide for early diagnosis and treatment.

Indexed as

Billroth II gastrectomyquantitative polymerase chain reactiontelomere length

Identifiers

PMID32399105
PMCPMC7212211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.