Evidence map›Paper›PMID 32399082›Full record

ReviewBehavioural neurology2020

Neuropsychological Changes in Complex Regional Pain Syndrome (CRPS).

Monika Halicka, Axel D Vittersø, Michael J Proulx, Janet H Bultitude

Open access · goldAbstract readReview
In one paragraph

Review in Behavioural neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Cognitive Function in Patients With Complex Regional Pain Syndrome (CRPS).European journal of pain (London, England) · 2025
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sensory Processing Patterns in People With Complex Regional Pain Syndrome.OTJR : occupation, participation and health · 2025
    Article
  8. Article
  9. Article
  10. Do menstrual symptoms affect motor imagery skills in young women?Archives of gynecology and obstetrics · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Monika HalickaCentre for Pain Research, University of Bath, Claverton Down Road, Bath BA2 7AY, UK.ORCID https://orcid.org/0000-0001-6283-9352
Axel D VittersøCentre for Pain Research, University of Bath, Claverton Down Road, Bath BA2 7AY, UK.
Michael J ProulxDepartment of Psychology, University of Bath, Claverton Down Road, Bath BA2 7AY, UK.ORCID https://orcid.org/0000-0003-4066-3645
Janet H BultitudeCentre for Pain Research, University of Bath, Claverton Down Road, Bath BA2 7AY, UK.ORCID https://orcid.org/0000-0003-4648-6184
University of Bath · GBUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex Regional Pain Syndrome (CRPS) is a poorly understood chronic pain condition of multifactorial origin. CRPS involves sensory, motor, and autonomic symptoms primarily affecting one extremity. Patients can also present with neuropsychological changes such as reduced attention to the CRPS-affected extremity, reminiscent of hemispatial neglect, yet in the absence of any brain lesions. However, this "neglect-like" framework is not sufficient to characterise the range of higher cognitive functions that can be altered in CRPS. This comprehensive literature review synthesises evidence of neuropsychological changes in CRPS in the context of potential central mechanisms of the disorder. The affected neuropsychological functions constitute three distinct but not independent groups: distorted body representation, deficits in lateralised spatial cognition, and impairment of non-spatially-lateralised higher cognitive functions. We suggest that many of these symptoms appear to be consistent with a broader disruption to parietal function beyond merely what could be considered "neglect-like." Moreover, the extent of neuropsychological symptoms might be related to the clinical signs of CRPS, and rehabilitation methods that target the neuropsychological changes can improve clinical outcomes in CRPS and other chronic pain conditions. Based on the limitations and gaps in the reviewed literature, we provide several suggestions to improve further research on neuropsychological changes in chronic pain.

Indexed as

AttentionChronic DiseaseCognitionComplex Regional Pain SyndromesFemaleHumansMaleNervous System DiseasesPainPain Measurement

Identifiers

PMID32399082
PMCPMC7201816
OpenAlexW2999763796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.