Evidence map›Paper›PMID 32399063›Full record

ArticleMobile DNA2020

Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin.

Eliza C Martin, Célia Vicari, Louis Tsakou-Ngouafo, Pierre Pontarotti, Andrei J Petrescu, David G Schatz

Open access · goldAbstract read
In one paragraph

Article in Mobile DNA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Eliza C Martin *1Department of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Splaiul Independentei 296, 060031 Bucharest, Romania.
Célia Vicari *2Evolutionary biology team, Aix Marseille Université IRD, APHM, MEPHI, IHU Méditerranée Infection, Marseille, France.
Louis Tsakou-Ngouafo2Evolutionary biology team, Aix Marseille Université IRD, APHM, MEPHI, IHU Méditerranée Infection, Marseille, France.
Pierre Pontarotti2Evolutionary biology team, Aix Marseille Université IRD, APHM, MEPHI, IHU Méditerranée Infection, Marseille, France.
Andrei J Petrescu1Department of Bioinformatics and Structural Biochemistry, Institute of Biochemistry of the Romanian Academy, Splaiul Independentei 296, 060031 Bucharest, Romania.
David G Schatz4Department of Immunobiology, Yale School of Medicine, 300 Cedar Street, Box 208011, New Haven, CT 06520-8011 USA.
Romanian Academy · ROAix-Marseille Université · FRInstitut de Recherche pour le Développement · FRMéditerranée Infection Foundation · FRYale University · US

Funding

Function and Evolutionary Origins of the RAG EndonucleaseR01AI137079 · NIAID · YALE UNIVERSITY · PI David G. Schatz · 2018 to 2026
$5.1M
NIAID NIH HHS R01 AI137079
6 · The paper itself

Abstract

backgroundV(D) J recombination is essential for adaptive immunity in jawed vertebrates and is initiated by the RAG1-RAG2 endonuclease. The

resultsWe have identified numerous

conclusionsActive

Indexed as

Adaptive immunityEvolutionRAGRecombination activating genesTransposonTransposon molecular domestication

Identifiers

PMID32399063
PMCPMC7204232
OpenAlexW3024911220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.