Evidence map›Paper›PMID 32398993›Full record

ArticleCurrent urology2020

"In-Bore" MRI-Guided Prostate Biopsy for Prostate Cancer Diagnosis: Results from 140 Consecutive Patients.

Daniele D'Agostino, Daniele Romagnoli, Marco Giampaoli, Federico Mineo Bianchi, Paolo Corsi, Alessandro Del Rosso, Riccardo Schiavina, Eugenio Brunocilla, Walter Artibani, Angelo Porreca

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Current urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
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  4. Targeted biopsy of the prostate.Abdominal radiology (New York) · 2025
    Review
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  6. Article
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  12. Review
  13. The combination of waterjet ablation (AquabeamCentral European journal of urology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Daniele D'AgostinoDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Daniele RomagnoliDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Marco GiampaoliDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Federico Mineo BianchiDepartment of Urology, University of Bologna, Bologna, Italy.
Paolo CorsiDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Alessandro Del RossoDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Riccardo SchiavinaDepartment of Urology, University of Bologna, Bologna, Italy.
Eugenio BrunocillaDepartment of Urology, University of Bologna, Bologna, Italy.
Walter ArtibaniDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Angelo PorrecaDepartment of Robotic Urological Surgery, Abano Terme Hospital, Abano Terme.
Policlinico Abano Terme · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTransrectal ultrasound-guided biopsy (TRUS-GB) is the current reference standard procedure for diagnosis of prostate cancer (PCa) but this procedure has limitations related to the low detection rate (DR) described in the literature. The aim of the study was to evaluate the DR efficiency, and complication rate in a pure "in-bore" magnetic resonance imaging-guided biopsy (MRI-GB) series according to the Prostate Imaging Reporting and Data System, version 2 (PI-RADS v2). MATERIALS AND

methodsFrom July 2015 to April 2018, a series of 142 consecutive patients undergoing MRI-GB were prospectively enrolled. According to the European Society of Urogenital Radiology guidelines, the presence of clinically significant PCa (csPCa) on multiparametric magnetic resonance imaging was defined as equivocal, likely, or highly likely according to a PI-RADS v2, score of 3, 4, or 5, respectively.

resultsOf 142 patients, 76 (53.5%) were biopsy naive and 66 (46.5%) had ≤ 1 previous negative set of random TRUS-GB findings. The MRI-GB findings were positive in 75 of 142 patients with a DR of 52.8%. Of the 76 patients with ≤ 1 previous set of TRUS-GB, 43 had PCa found by MRI-GB, with a DR of 57.3%. The DR in the 66 biopsy-naive patients was 48% (32/66). Of the 75 patients with positive biopsy findings, 54 (80.5%) were found to have csPCa on histological examination. Of these 54 patients, 28 had an International Society of Urological Pathology grade 2; 5 had grade 3, 19 had grade 4, and 2 had grade 5. Considering the anatomic distribution of the index lesions using the PI-RADS v2 scheme, the probability of PCa was greater for lesions located in the peripheral zone (55 of 75, 73.3%) than for those in the central zone (20 of 75, 26.7%).

conclusionsOur study conducted on 142 patients confirmed the greater DR of csPCa by MRI-GB, with a very low number of cores needed and a negligible incidence of complications, especially in patients with a previous negative biopsy. MRI-GB is optimal for the diagnosis of anterior and central lesions.

Indexed as

Multiparametric magnetic resonanceProstate biopsyProstate cancerProstate cancer detectionTransrectal ultrasound-guided prostate biopsy

Identifiers

PMID32398993
PMCPMC7206582
OpenAlexW3012474100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.