ArticleBreast care (Basel, Switzerland)2020
Factors Influencing the Onset of Neoadjuvant Therapy in Breast Cancer Patients.
Article in Breast care (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The Impact of Staging Investigations in HER2-Low, Low-Risk Patients.Breast care (Basel, Switzerland) · 2026Article
- Can Ki-67 serve as a suitable marker to indicate the necessity of staging diagnostics in cases of low-risk breast cancer?Archives of gynecology and obstetrics · 2025Article
- Diagnostic performance of additional imaging tests for staging purposes in a bicentric German series of low-risk early breast cancer patients.Archives of gynecology and obstetrics · 2024Article
- Influences on pathologic complete response in breast cancer patients after neoadjuvant chemotherapy.Archives of gynecology and obstetrics · 2021Article
- Factors influencing the time to surgery after neoadjuvant chemotherapy in breast cancer patients.Archives of gynecology and obstetrics · 2020Article
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Authors and funding
6 authors.
Funding
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Abstract
backgroundTime to treatment onset (TTTO) is critical in breast cancer patients receiving neoadjuvant chemotherapy (NACT). We therefore investigated possible delaying factors of therapy onset.
methodsAll patients were included who qualified for NACT in our hospital from 2015 to 2017. The time interval between core biopsy of tumor and date of therapy onset was defined as primary endpoint. Among other things, age, out- and in-patient presentation, and study or standard treatment were investigated as potentially delaying factors.
resultsWe analyzed 139 patients scheduled for NACT; 90 (64.7%) received standard NACT, and 49 (35.3%) were recruited for trials. The average age was 53 years (±13.2 years). A time interval of 30.7 days (±11.8 days) was seen between diagnosis and therapy onset. Patients had a mean of 5 (±1.9) pretherapeutic presentations, 4 (±1.8) on outpatient and 1 (±0.5) on inpatient basis, being of significant influence on TTTO.
conclusionAny outpatient presentation extended the time interval by 2 days, inpatient presentation by 4 days. These presentations should be merged in order to minimize TTTO. Neither the site of pathology examinations, additional consultations (genetics, reproductive medicine), nor study participation delayed therapy onset.
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