Evidence map›Paper›PMID 32398779›Full record

ArticleJournal of exposure science & environmental epidemiology2020

The association between residential proximity to brownfield sites and high-traffic areas and measures of immunity.

Evans K Lodge, Lawrence S Engel, Sara Ferrando-Martínez, Derek Wildman, Monica Uddin, Sandro Galea, Allison E Aiello

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Living Near Contamination: The Impacts on Personal Well-Being.Applied research in quality of life · 2025
    Article
  6. Article
  7. Article
  8. A Multiscale Spatiotemporal Epidemiological Analysis of Neighborhood Correlates of Triple-Negative Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evans K LodgeDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lawrence S EngelDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sara Ferrando-MartínezEarly Oncology, Discover ICA, AstraZeneca, Gaithersburg, MD, USA.
Derek WildmanCollege of Public Health, University of South Florida, Tampa, FL, USA.
Monica UddinCollege of Public Health, University of South Florida, Tampa, FL, USA.
Sandro GaleaSchool of Public Health, Boston University, Boston, MA, USA.
Allison E AielloDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. aaiello@email.unc.edu.ORCID http://orcid.org/0000-0001-7029-2537

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008719 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DARVILLE, TONI, DESHMUKH, MOHANISH P · 1999 to 2023
$15.1M
POPULATION STUDIEST32HD007168 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 1985 to 2026
$13.8M
Research DevelopmentP30AG013283 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MILLER, RICHARD A · 1995 to 2014
$12.3M
Epigenomic Predictors of PTSD and Traumatic Stress in an African American CohortR01MD011728 · NIMHD · UNIVERSITY OF SOUTH FLORIDA · PI AIELLO, ALLISON E, UDDIN, MONICA · 2017 to 2025
$5.7M
Ecologic Stressors, PTSD, and Drug Use in DetroitR01DA022720 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI AIELLO, ALLISON E · 2007 to 2011
$4.7M
NIA NIH HHS P30 AG013283NICHD NIH HHS T32 HD007168NIDA NIH HHS R01 DA022720NIEHS NIH HHS P30 ES010126NIEHS NIH HHS T32 ES007018NIGMS NIH HHS T32 GM008719NIMHD NIH HHS R01 MD011728
6 · The paper itself

Abstract

The mechanisms by which neighborhood environmental exposures influence health are poorly understood, although immune system dysregulation represents a potential biological pathway. While many neighborhood exposures have been investigated, there is little research on residential proximity to brownfield waste. Using biomarker data from 262 participants in the Detroit Neighborhood Health Study, we estimated the association between proximity to brownfields and heavy traffic and signal joint T-cell receptor excision circles (sjTRECs, a measure of naive T-cell production), C-reactive protein (CRP, a measure of systemic inflammation), and interleukin-6 (IL-6, a pro-inflammatory cytokine). We assessed residential proximity ≤200 m from brownfields and highways on all three biomarkers using multivariate regression. We demonstrated that living ≤200 m from a brownfield site was associated with a 0.30 (95% CI = 0.59, 0.02, p = 0.04) log

Indexed as

Air PollutantsEnvironmental ExposureBiomarkersC-Reactive ProteinHazardous SubstancesHumansInflammationVehicle EmissionsAir PollutantsBiomarkersC-Reactive ProteinHazardous SubstancesVehicle EmissionsEnvironmental monitoringEpidemiologyExposure modelingPersonal exposurePopulation-based studies

Identifiers

PMID32398779
PMCPMC7483819

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.