Evidence map›Paper›PMID 32398755›Full record

ArticleInternational journal of obesity (2005)2020

No evidence for an association between obesity and milkshake liking.

Kathryn M Wall, Michael C Farruggia, Emily E Perszyk, Arsene Kanyamibwa, Sophie Fromm, Xue S Davis, Jelle R Dalenberg, Alexandra G DiFeliceantonio, Dana M Small

Open access · greenAbstract read
In one paragraph

Article in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Homeostatic regulation of food intake.Clinics and research in hepatology and gastroenterology · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kathryn M WallDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.ORCID http://orcid.org/0000-0002-0519-9739
Michael C FarruggiaDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.ORCID http://orcid.org/0000-0002-5306-6754
Emily E PerszykDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.ORCID http://orcid.org/0000-0002-8902-4644
Arsene KanyamibwaDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.
Sophie FrommDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.
Xue S DavisDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.
Jelle R DalenbergDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.
Alexandra G DiFeliceantonioDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA.
Dana M SmallDepartment of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT, 06511, USA. dana.small@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The role of the amygdala in weight gain susceptibilityR01DK085579 · NIDDK · JOHN B. PIERCE LABORATORY, INC. · PI DE ARAUJO, IVAN E, SMALL, DANA M · 2010 to 2014
$3.6M
(PQA3) The gut-brain axis: a novel target for treating behavioral alterations inR01CA180030 · NCI · JOHN B. PIERCE LABORATORY, INC. · PI DE ARAUJO, IVAN E, SMALL, DANA M · 2013 to 2016
$2.6M
NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA180030NIDDK NIH HHS R01 DK085579
6 · The paper itself

Abstract

backgroundPrevailing models of obesity posit that hedonic signals override homeostatic mechanisms to promote overeating in today's food environment. What researchers mean by "hedonic" varies considerably, but most frequently refers to an aggregate of appetitive events including incentive salience, motivation, reinforcement, and perceived pleasantness. Here we define hedonic as orosensory pleasure experienced during eating and set out to test whether there is a relationship between adiposity and the perceived pleasure of a palatable and energy-dense milkshake.

methodsThe perceived liking, wanting, and intensity of two palatable and energy-dense milkshakes were assessed using the Labeled Hedonic Scale (1), visual analog scale (VAS), and Generalized Labeled Magnitude Scale (2) in 110 individuals ranging in body mass index (BMI) from 19.3 to 52.1 kg/m

resultsWe identified a significant association between ratings of hunger and milkshake liking and wanting. By contrast, we found no evidence for a relationship between any measure of adiposity and ratings of milkshake liking, wanting, or intensity.

conclusionsWe conclude that adiposity is not associated with the pleasure experienced during consumption of our energy-dense and palatable milkshakes. Our results provide further evidence against the hypothesis that heightened hedonic signals drive weight gain.

Indexed as

Food PreferencesAdultDairy ProductsEmotionsFemaleHumansHungerMagnetic Resonance ImagingMaleMotivationObesityYoung Adult

Identifiers

PMID32398755
PMCPMC7387147
OpenAlexW3024178335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.