Evidence map›Paper›PMID 32398372›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice.

Shayne D Wierbowski, Tommy V Vo, Pascal Falter-Braun, Timothy O Jobe, Lars H Kruse, Xiaomu Wei, Jin Liang, Michael J Meyer, Nurten Akturk, Christen A Rivera-Erick and 20 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Shayne D WierbowskiDepartment of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-2595-2011
Tommy V VoWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Pascal Falter-BraunInstitute of Network Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Munich, Germany.ORCID 0000-0003-2012-6746
Timothy O JobeBotanical Institute, Cluster of Excellence on Plant Sciences (CEPLAS), University of Cologne, 50674 Cologne, Germany.ORCID 0000-0002-5729-4981
Lars H KrusePlant Biology Section, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-0449-092X
Xiaomu WeiDepartment of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853.
Jin LiangWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Michael J MeyerDepartment of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853.
Nurten AkturkWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Christen A Rivera-ErickWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Nicolas A CorderoWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-6443-3089
Mauricio I ParamoWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-9518-1881
Elnur E ShayhidinWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Marta BertolottiWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853.
Nathaniel D TippensDepartment of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-4377-8691
Kazi AktherSection of Plant Breeding and Genetics, School of Integrated Plant Sciences, Cornell University, Ithaca, NY 14853-1901.
Rita SharmaSchool of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi 110067, India.
Yuichi KatayoseAdvanced Genomics Breeding Section, Institute of Crop Science, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8634, Japan.ORCID 0000-0002-4500-3964
Kourosh Salehi-AshtianiLaboratory of Algal, Systems, and Synthetic Biology, Division of Science and Math, New York University Abu Dhabi, 129188, Abu Dhabi, United Arab Emirates.ORCID 0000-0002-6521-5243
Tong HaoCenter for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
Pamela C RonaldDepartment of Plant Pathology, University of California, Davis, CA 95616.ORCID 0000-0002-4107-1345
Joseph R EckerHoward Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037.ORCID 0000-0001-5799-5895
Peter A SchweitzerBRC Genomics Facility, Institute of Biotechnology, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-4525-7013
Shoshi KikuchiPlant Genome Research Unit, Division of Genome and Biodiversity Research, Agrogenomics Research Center, National Institute of Agrobiological Sciences, Tsukuba 305-0856, Japan.
Hiroshi MizunoDepartment of Molecular Biology, National Institute of Agrobiological Resources, Tsukuba 305-0856, Japan.
David E HillCenter for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215.ORCID 0000-0001-5192-0921
Marc VidalCenter for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02215.
Gaurav D MoghePlant Biology Section, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-8761-064X
Susan R McCouchSection of Plant Breeding and Genetics, School of Integrated Plant Sciences, Cornell University, Ithaca, NY 14853-1901; srm4@cornell.edu haiyuan.yu@cornell.edu.ORCID 0000-0001-9246-3106
Haiyuan YuDepartment of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853; srm4@cornell.edu haiyuan.yu@cornell.edu.ORCID 0000-0001-7597-6049

Funding

Integrated high-throughput functional assays to identify ulcerative colitis causal risk variantsR01DK115398 · NIDDK · CORNELL UNIVERSITY · PI KLEIN, ROBERT J., YU, HAIYUAN · 2018 to 2022
$3.3M
Quantifying molecular consequences of human missense variants with large-scale interactome perturbation studiesR01GM125639 · NIGMS · CORNELL UNIVERSITY · PI ALEXOV, EMIL GEORGIEV, CLARK, ANDREW G · 2018 to 2021
$2.6M
Activation of immune receptor signaling by a sulfated peptideR01GM122968 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RONALD, PAMELA C · 2017 to 2020
$2.1M
Towards a comprehensive multiscale 3D human interactome networkR01GM124559 · NIGMS · CORNELL UNIVERSITY · PI YU, HAIYUAN · 2017 to 2020
$1.5M
Howard Hughes Medical InstituteNIDDK NIH HHS R01 DK115398NIGMS NIH HHS R01 GM122968NIGMS NIH HHS R01 GM124559NIGMS NIH HHS R01 GM125639
6 · The paper itself

Abstract

Systematic mappings of protein interactome networks have provided invaluable functional information for numerous model organisms. Here we develop

Indexed as

Computational BiologyDatabases, GeneticDNA, PlantGenome, PlantHigh-Throughput Nucleotide SequencingOpen Reading FramesOryzaProtein Interaction MappingProtein Interaction MapsSequence Analysis, DNADNA, Plantnetworksnext-generation sequencingORFeomeprotein–protein interactionrice

Identifiers

PMID32398372
PMCPMC7260977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.