Evidence map›Paper›PMID 32398314›Full record

ArticlemBio2020

Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection.

Seo J Park, Rachel E Riccio, Sarah J Kopp, Igal Ifergan, Stephen D Miller, Richard Longnecker

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. The role of PPAR in fungal keratitis.Frontiers in immunology · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Seo J ParkDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Rachel E RiccioDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Sarah J KoppDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Igal IferganDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Stephen D MillerDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Richard LongneckerDepartment of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA r-longnecker@northwestern.edu.ORCID 0000-0001-7175-6217
Northwestern University · US

Funding

IMMUNOREGULATION AND PATHOLOGY OF CHRONIC-RELAPSING EAER01NS026543 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MILLER, STEPHEN D · 1988 to 2016
$5.0M
Role of Host Cell Factors in Herpes Simplex Virus (HSV) KeratitisR01EY023977 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LONGNECKER, RICHARD M · 2016 to 2019
$1.5M
NEI NIH HHS R01 EY023977NINDS NIH HHS R01 NS026543
6 · The paper itself

Abstract

Ocular herpes simplex virus 1 (HSV-1) infection leads to an immunopathogenic disease called herpes stromal keratitis (HSK), in which CD4

Indexed as

Virus InternalizationAnimalsCorneaDisease Models, AnimalFemaleHerpesvirus 1, HumanHost Microbial InteractionsInflammationKeratitis, HerpeticMaleMice, Inbred C57BLMice, KnockoutReceptors, Tumor Necrosis Factor, Member 14Signal TransductionT-LymphocytesReceptors, Tumor Necrosis Factor, Member 14BTLACD160herpesvirus stromal keratitisHSVHVEMimmunopathogenesisLIGHT

Identifiers

PMID32398314
PMCPMC7218284
OpenAlexW3025943486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.