Evidence map›Paper›PMID 32398311›Full record

ArticlemBio2020

Mutations in

Jeffrey M Rybak, José F Muñoz, Katherine S Barker, Josie E Parker, Brooke D Esquivel, Elizabeth L Berkow, Shawn R Lockhart, Lalitha Gade, Glen E Palmer, Theodore C White and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 1 synthesis or guideline pooled it, 190 citations in OpenAlex.

  1. Global characteristics and trends in research onFrontiers in microbiology · 2023
    Pooled it
  2. Article
  3. A novelMicrobiology spectrum · 2026
    Article
  4. Beyond intrinsic resistance: novel insights into the emergence and management of resistance acquired in Candida auris upon antifungal exposure.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  5. Review
  6. hLife · 2026
    Article
  7. Emergence and Comparative Analysis ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  8. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Deciphering the multidrug resistance paradigm inAntimicrobial agents and chemotherapy · 2026
    Review
  13. Microbiology and molecular biology reviews : MMBR · 2026
    Review
  14. Article
  15. Article
  16. Review
  17. Relative contributions of the ERG11Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2026
    Article
  18. Comprehensive Insights into Sugar Transporters ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  19. Review
  20. Genomic Insights intoJournal of fungi (Basel, Switzerland) · 2026
    Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Jeffrey M RybakDepartment of Clinical Pharmacy and Translational Science, University of Tennessee College of Pharmacy, Memphis, Tennessee, USA.ORCID 0000-0002-9317-0935
José F MuñozBroad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.ORCID 0000-0003-4987-7957
Katherine S BarkerDepartment of Clinical Pharmacy and Translational Science, University of Tennessee College of Pharmacy, Memphis, Tennessee, USA.
Josie E ParkerCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, United Kingdom.
Brooke D EsquivelSchool of Biological Sciences, University of Missouri at Kansas City, Kansas City, Missouri, USA.ORCID 0000-0001-7328-4057
Elizabeth L BerkowMycotic Diseases Branch, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Shawn R LockhartMycotic Diseases Branch, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Lalitha GadeMycotic Diseases Branch, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Glen E PalmerDepartment of Clinical Pharmacy and Translational Science, University of Tennessee College of Pharmacy, Memphis, Tennessee, USA.
Theodore C WhiteSchool of Biological Sciences, University of Missouri at Kansas City, Kansas City, Missouri, USA.
Steve L KellyCentre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, United Kingdom.
Christina A CuomoBroad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.ORCID 0000-0002-5778-960X
P David RogersDepartment of Clinical Pharmacy and Translational Science, University of Tennessee College of Pharmacy, Memphis, Tennessee, USA drogers@uthsc.edu.
University of Tennessee Health Science Center · USCenters for Disease Control and Prevention · USBroad Institute · USSwansea University · GBUniversity of Missouri–Kansas City · US

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI NEAFSEY, DANIEL E · 2014 to 2024
$66.5M
Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
Upc2A: A Central Regulator and "Achilles' Heel" of Fluconazole Resistance in Candida glabrataR01AI131620 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2017 to 2021
$2.7M
NIAID NIH HHS R01 AI058145NIAID NIH HHS R01 AI131620NIAID NIH HHS U19 AI110818
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsCandidaDrug Resistance, FungalFluconazoleFungal ProteinsMicrobial Sensitivity TestsMutationTranscription FactorsAntifungal AgentsFluconazoleFungal ProteinsTranscription Factorsantifungal resistanceCandidaCRISPRdrug effluxeffluxresistancetriazoleWGS

Identifiers

PMID32398311
PMCPMC7218281
OpenAlexW3025731814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.