Evidence map›Paper›PMID 32398162›Full record

ReviewHuman genomics2020

COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission.

Krystal J Godri Pollitt, Jordan Peccia, Albert I Ko, Naftali Kaminski, Charles S Dela Cruz, Daniel W Nebert, Juergen K V Reichardt, David C Thompson, Vasilis Vasiliou

Abstract readReview
In one paragraph

Review in Human genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  14. The Wavelength-Based Inactivation Effects of a Light-Emitting Diode Module on Indoor Microorganisms.International journal of environmental research and public health · 2022
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Krystal J Godri PollittDepartment of Environmental Health Sciences, School of Public Health, Yale University, New Haven, CT, 06510, USA. krystal.pollitt@yale.edu.
Jordan PecciaDepartment of Chemical & Environmental Engineering, School of Engineering & Applied Science, Yale University, New Haven, CT, 06520, USA.
Albert I KoDepartment of Epidemiology of Microbial Diseases, School of Public Health, Yale University, New Haven, CT, 06510, USA.
Naftali KaminskiSection of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, Yale University, New Haven, CT, 06520, USA.
Charles S Dela CruzSection of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, Yale University, New Haven, CT, 06520, USA.
Daniel W NebertDepartment of Environmental Health and Center for Environmental Genetics, University Cincinnati Medical Center, Cincinnati, OH, 45267, USA.
Juergen K V ReichardtAustralian Institute of Tropical Health and Medicine, James Cook University, Smithfield, QLD, Australia.
David C ThompsonDepartment of Clinical Pharmacy, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of Colorado Denver, Aurora, CO, 80045, USA.
Vasilis VasiliouDepartment of Environmental Health Sciences, School of Public Health, Yale University, New Haven, CT, 06510, USA. vasilis.vasiliou@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The recent coronavirus disease (COVID-19), caused by SARS-CoV-2, is inarguably the most challenging coronavirus outbreak relative to the previous outbreaks involving SARS-CoV and MERS-CoV. With the number of COVID-19 cases now exceeding 2 million worldwide, it is apparent that (i) transmission of SARS-CoV-2 is very high and (ii) there are large variations in disease severity, one component of which may be genetic variability in the response to the virus. Controlling current rates of infection and combating future waves require a better understanding of the routes of exposure to SARS-CoV-2 and the underlying genomic susceptibility to this disease. In this mini-review, we highlight possible genetic determinants of COVID-19 and the contribution of aerosol exposure as a potentially important transmission route of SARS-CoV-2.

Indexed as

Air MicrobiologyGenetic Predisposition to DiseaseBetacoronavirusCoronavirus InfectionsCOVID-19Disease Transmission, InfectiousHumansPandemicsPersonal Protective EquipmentPneumonia, ViralSARS-CoV-2

Identifiers

PMID32398162
PMCPMC7214856

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.