Evidence map›Paper›PMID 32398114›Full record

ArticleJournal of foot and ankle research2020

Does the application of Opsite

A Beaumont, L McSorley, M Matthews, K Mooneesawmy, L Little, J R Forss

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Journal of foot and ankle research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

A BeaumontCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK.
L McSorleyCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK.
M MatthewsCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK.
K MooneesawmyCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK.
L LittleCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK.
J R ForssCentre for Regenerative Medicine and Devices, University of Brighton, 49 Darley Road, Eastbourne, BN20 7UR, UK. J.Forss@brighton.ac.uk.ORCID http://orcid.org/0000-0002-7098-9710
University of Brighton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA proportion of people who have been diagnosed with peripheral arterial disease and diabetes mellitus will be susceptible to chronic wounds. Oxygen is vital for wound healing, so oxygen measurements should to be taken as predictive values for wound healing in patients. When measuring oxygen at the wound bed, there is potentially a risk of cross-infection if no protective barrier is used; and skin stripping if an adhesive barrier is used on the wound bed. This cross sectional within subject repeated measures pilot study, aims to determine if the application of opsite film, as an infection control measure, in one or two layers, impacts on tissue oxygenation readings obtained when using the MoorVMS-OXY.

methodsMean oxygen saturation percentages were measured from 29 limbs of 18 healthy participants. Oxygen saturation was measured for 20 s and analysed at the first metatarsophalangeal joint using no film, one and two layers using the MoorVMS-OXY. A one-way repeated ANOVA with a Bonferroni post hoc test was performed to test for statistically significant differences between the values of the three parameters and multiple pairwise comparisons was completed.

resultsAmongst the three layers, there was a statistically significant difference in oxygen saturation between the two layers of Opsite Flexigrid and none; and also between the two layers of Flexigrid and single layer (p < 0.05). It was also established that there was no statistically significant difference between the single layer of Opsite Flexigrid and no Flexigrid layer (p > 0.05).

conclusionsThe results imply that one layer of Opsite Flexigrid is a suitable protective barrier to use when establishing capillary bed oxygen perfusion with the MoorVMS-OXY. However, the application of two Opsite Flexigrid layers, to prevent skin stripping, decreases the recorded values of oxygen saturation percentages significantly, therefore providing inaccurate results. Indicating that a double layer cannot be used over ulceration sites if measuring oxygen levels at the wound bed.

Indexed as

Wound HealingAdultCross InfectionCross-Sectional StudiesData AccuracyFemaleFoot UlcerHealthy VolunteersHumansMaleMetatarsophalangeal JointMiddle AgedOximetryOxygenOxygen ConsumptionPilot ProjectsOpsitureOxygenPolyurethanesCross-infectionFirst metatarsophalangeal jointMoorVMS-OXYOpsite FlexigridOxygen saturation percentagesSkin stripping

Identifiers

PMID32398114
PMCPMC7216319
OpenAlexW3028487905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.