Evidence map›Paper›PMID 32397975›Full record

SynthesisBMC public health2020

Interventions to support people exposed to adverse childhood experiences: systematic review of systematic reviews.

Theo Lorenc, Sarah Lester, Katy Sutcliffe, Claire Stansfield, James Thomas

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07118072 (Internet-Delivered Skills Training in Affective and Interpersonal Regulation), which is not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07118072 narecruitingnot on this mapstarted 2025, after this paper: background citation

Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression: A Pilot Study

TypeinterventionalSponsorInstitute of Mental Health, SingaporeRan2025 to 2028Enrolled150ConditionsSubthreshold DepressionArmsInternet-Delivered Skills Training in Affective and Interpersonal Regulation, Online general psychoeducation
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Childhood adversity and trajectories of health and quality of life in Australian children and adolescents: a latent class analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Differential effects of childhood maltreatment types and timing on psychopathology in formerly out-of-home placed young adults.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  16. Article
  17. Article
  18. Protective factors for adverse childhood experiences: Scoping review and evidence gap map.Psychological trauma : theory, research, practice and policy · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Theo LorencCentre for Reviews & Dissemination, University of York, York, YO10 5DD, UK. theo.lorenc@york.ac.uk.ORCID http://orcid.org/0000-0001-8937-6378
Sarah LesterEPPI-Centre, Social Science Research Unit, Institute of Education, University College London, 18 Woburn Square, London, WC1H 0NR, UK.
Katy SutcliffeEPPI-Centre, Social Science Research Unit, Institute of Education, University College London, 18 Woburn Square, London, WC1H 0NR, UK.
Claire StansfieldEPPI-Centre, Social Science Research Unit, Institute of Education, University College London, 18 Woburn Square, London, WC1H 0NR, UK.
James ThomasEPPI-Centre, Social Science Research Unit, Institute of Education, University College London, 18 Woburn Square, London, WC1H 0NR, UK.
University College London · GBKleijnen Systematic Reviews (United Kingdom) · GB

Funding

National Institute for Health Research Policy Research Programme
6 · The paper itself

Abstract

backgroundAdverse Childhood Experiences (ACEs) such as abuse, neglect or household adversity may have a range of serious negative impacts. There is a need to understand what interventions are effective to improve outcomes for people who have experienced ACEs.

methodsSystematic review of systematic reviews. We searched 18 database sources from 2007 to 2018 for systematic reviews of effectiveness data on people who experienced ACEs aged 3-18, on any intervention and any outcome except incidence of ACEs. We included reviews with a summary quality score (AMSTAR) of 5.5 or above.

resultsTwenty-five reviews were included. Most reviews focus on psychological interventions and mental health outcomes. The strongest evidence is for cognitive-behavioural therapy for people exposed to abuse. For other interventions - including psychological therapies, parent training, and broader support interventions - the findings overall are inconclusive, although there are some positive results.

conclusionsThere are significant gaps in the evidence on interventions for ACEs. Most approaches focus on mitigating individual psychological harms, and do not address the social pathways which may mediate the negative impacts of ACEs. Many negative impacts of ACEs (e.g. on health behaviours, social relationships and life circumstances) have also not been widely addressed by intervention studies.

Indexed as

Resilience, PsychologicalAdolescentAdultAdverse Childhood ExperiencesAgedAged, 80 and overChildChild AbuseChild, PreschoolFemaleHumansMaleMiddle AgedSurvivorsAdverse childhood experiencesChild abuseResilience, psychologicalSystematic review

Identifiers

PMID32397975
PMCPMC7216383
OpenAlexW3025740195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.