Evidence map›Paper›PMID 32397739›Full record

ReviewCephalalgia : an international journal of headache2020

Cluster headache in Asian populations: Similarities, disparities, and a narrative review of the mechanisms of the chronic subtype.

Kuan-Po Peng, Tsubasa Takizawa, Mi Ji Lee

Open access · hybridAbstract readReview
In one paragraph

Review in Cephalalgia : an international journal of headache, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  4. Observational
  5. Article
  6. Non-Invasive Vagus Nerve Stimulation in Cluster Headache: A Clinical Practice Guideline.Pain practice : the official journal of World Institute of Pain · 2025
    Review
  7. Hallmarks of primary headache: part 3 - cluster headache.The journal of headache and pain · 2025
    Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Kuan-Po PengDepartment of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-2718-3738
Tsubasa TakizawaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Mi Ji LeeDepartment of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.ORCID 0000-0003-1364-1969
Keio University · JPNational Yang Ming Chiao Tung University · TWSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeadache disorders like migraine show geographic and ethnic differences between Asian and European/North American countries. In cluster headache, these differences are rarely mentioned and discussed. This article aimed to review the characteristics of cluster headache in Asian countries and compare the clinical features to those in European and North American populations.

methodsWe conducted a narrative literature review on the demographics, clinical presentations, and treatments of cluster headache in Asian countries.

resultsPatients with cluster headache in Asian populations showed a stronger male predominance compared to European and North American populations. Chronic cluster headache was rare in Asian countries. The clinical presentation of restlessness was not as common in Asian as it was in European and North American countries, and Asian patients with aura were extremely rare. Patients in Asian countries may have a lower circadian rhythmicity of cluster headache and a lower headache load, as demonstrated by lower attack frequencies per day, bout frequencies, and bout durations.

conclusionsRegional differences in the presentation of cluster headache exist. Greater awareness for cluster headache should be raised in Asian regions, and further studies are warranted to elucidate the mechanisms behind observed differences.

Indexed as

Cluster HeadacheAsian PeopleFemaleHumansMaleAsianchronic cluster headacheChronobiologydisease load

Identifiers

PMID32397739
PMCPMC7457455
OpenAlexW3024212705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.