ReviewInternational journal of molecular sciences2020
Gender-Related Approach to Kidney Cancer Management: Moving Forward.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 72 citations in OpenAlex.
- Clinicohistopathological characteristics of renal cell carcinoma in Jordan.Future science OA · 2026Article
- Medicaid Expansion and Overall Mortality Among Individuals With Renal Cell Carcinoma.The Journal of surgical research · 2026Article
- Trends in kidney and renal pelvis cancer mortality and associated risk factors in the United States.BMC public health · 2025Article
- Temporal trends and demographic-geographic disparities in kidney Cancer mortality in the United States, 1999-2023.Preventive medicine reports · 2025Article
- Changes in the Characteristics of Kidney Cancer Detection During the COVID-19 Pandemic.Cancers · 2025Article
- Rising incidence and clinical impact of kidney cancer in China and worldwide: a call for targeted prevention, early diagnosis, and equitable treatment.Translational andrology and urology · 2025Article
- Survival outcomes and risk factors for liver and pancreatic metastases in renal cell carcinoma after curative nephrectomy.BMC urology · 2025Article
- Trends in kidney cancer: exploring the impact of sex and age on stage of disease, and prognosis during the past three decades in Denmark-a DaRenCa study.European journal of epidemiology · 2025Article
- Advancements in high-intensity focused ultrasound for urological tumor research and application.Annals of medicine and surgery (2012) · 2025Review
- Prognostic factors and nomogram development for survival in renal cell carcinoma patients with multiple primary cancers: a retrospective study.Translational andrology and urology · 2025Article
- Age-sex-specific burden of urological cancers attributable to risk factors in China and its provinces, 1990-2021, and forecasts with scenarios simulation: a systematic analysis for the Global Burden of Disease Study 2021.The Lancet regional health. Western Pacific · 2025Article
- The correlation between serum sex hormone levels and clear cell renal cell carcinoma in male patients.Scientific reports · 2025Article
- Global Burden of Kidney Cancer Attributable to High Body Mass Index in Adults Aged 60 and Older from 1990 to 2021 and Projections to 2040: A Systematic Analysis for the Global Burden of Disease Study.Clinical epidemiology · 2025Article
- Nrf2 Signaling in Renal Cell Carcinoma: A Potential Candidate for the Development of Novel Therapeutic Strategies.International journal of molecular sciences · 2024Review
- Prognostic value of B7-H3 expression in metastatic renal cell carcinoma and its impact on immunotherapy response.BMC cancer · 2024Article
- In Vivo and In Vitro Response to a Regenerative Dental Scaffold.Materials (Basel, Switzerland) · 2024Article
- Estimated cost of VEGFR TKI associated adverse events in metastatic renal cell carcinoma patients.BMC health services research · 2024Article
- Review
- Can Cytoreductive Nephrectomy Improve Outcomes of Nivolumab Treatment in Patients with Metastatic Clear-Cell Renal Carcinoma?Current oncology (Toronto, Ont.) · 2024Article
- Tissue Ablation: Applications and Perspectives.Advanced materials (Deerfield Beach, Fla.) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Men are more frequently diagnosed with kidney cancer than women, with a more aggressive histology, larger tumors, a higher grade and stage, and worse oncological outcomes. Smoking habits and sex steroid hormones seem to have a possible role in explaining these gender disparities. Moreover, the expression of genes involved in tumor growth and immune response in kidney cancer varies between men and women, having an impact on the gender-related response to oncological therapy, such as anti-angiogenic drugs and immunotherapy. Recent advances have been made in our understanding of the molecular and genetic mechanisms involved in kidney cancer, which could partially explain the gender differences, and they are summarized in this paper. However, other key mechanisms, which fully clarify the striking clinical gender-related differences observed in kidney cancer, are not completely understood at present. We reviewed and summarized the most relevant publications about the relationship between gender and kidney cancer. Efforts should be made to progress in bench and clinical research on gender-related signatures and disparities, and their impact on the clinical management of kidney cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.