Evidence map›Paper›PMID 32397647›Full record

ArticleMolecules (Basel, Switzerland)2020

Conserved Dynamic Mechanism of Allosteric Response to L-arg in Divergent Bacterial Arginine Repressors.

Saurabh Kumar Pandey, Milan Melichercik, David Řeha, Rüdiger H Ettrich, Jannette Carey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Saurabh Kumar PandeyCenter for Nanobiology and Structural Biology, Institute of Microbiology, Czech Academy of Sciences, 37333 Nove Hrady, Czechia.
Milan MelichercikCenter for Nanobiology and Structural Biology, Institute of Microbiology, Czech Academy of Sciences, 37333 Nove Hrady, Czechia.
David ŘehaCenter for Nanobiology and Structural Biology, Institute of Microbiology, Czech Academy of Sciences, 37333 Nove Hrady, Czechia.
Rüdiger H EttrichCenter for Nanobiology and Structural Biology, Institute of Microbiology, Czech Academy of Sciences, 37333 Nove Hrady, Czechia.ORCID 0000-0001-8624-7706
Jannette CareyCenter for Nanobiology and Structural Biology, Institute of Microbiology, Czech Academy of Sciences, 37333 Nove Hrady, Czechia.
Czech Academy of Sciences · CZFlorida International University · USPrinceton University · US

Funding

Agentúra na Podporu Výskumu a Vývoja APVV-16-0600Grantová Agentura České Republiky 13-21053SMinisterstvo Školství, Mládeže a Tělovýchovy LM2010005Ministerstvo Školství, Mládeže a Tělovýchovy LM2015055MoA between the Institute of Microbiology, Czech Academy of Sciences, and the College of Biomedical Sciences, Larkin University. 2018National Science Foundation DBI13-58737National Science Foundation DBI16-59726
6 · The paper itself

Abstract

Hexameric arginine repressor, ArgR, is the feedback regulator of bacterial L-arginine regulons, and sensor of L-arg that controls transcription of genes for its synthesis and catabolism. Although ArgR function, as well as its secondary, tertiary, and quaternary structures, is essentially the same in

Indexed as

Allosteric RegulationAmino Acid SequenceArginineBacillus subtilisBacterial ProteinsEntropyEscherichia coliHydrogen BondingMolecular Dynamics SimulationPhylogenyProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein DomainsRegulonRepressor ProteinsArginineArgR protein, BacteriaBacterial ProteinsRepressor Proteinsentropyglobal motionligand bindingmolecular evolutionsalt bridges

Identifiers

PMID32397647
PMCPMC7248756
OpenAlexW3022171566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.