ArticlePathogens (Basel, Switzerland)2020
Characterizing Peri-Implant and Sub-Gingival Microbiota through Culturomics. First Isolation of Some Species in the Oral Cavity. A Pilot Study.
Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Exploring the oral microbiome: from traditional techniques to advanced omics and databases.Antonie van Leeuwenhoek · 2026Review
- Isolation of phages against Streptococcus species in the oral cavity for potential control of dental diseases and associated systemic complications.Archives of microbiology · 2024Article
- Omics for deciphering oral microecology.International journal of oral science · 2024Review
- Comparison between twin block appliance and mandibular advancement on clear aligners in the improvement of airway dimension: incremental versus maximum bite advancement.Frontiers in oral health · 2024Article
- Oral microbiota may predict the presence of esophageal squamous cell carcinoma.Journal of cancer research and clinical oncology · 2023Article
- Rummeliibacillus suwonensis: First Time Isolation from Human Feces by Culturomics.Current microbiology · 2022Article
- "Bacterial Consortium": A Potential Evolution of Fecal Microbiota Transplantation for the Treatment ofBioMed research international · 2022Article
- Cultivation and Genomic Characterization of the Bile Bacterial Species From Cholecystitis Patients.Frontiers in microbiology · 2021Article
- Cleaning Teeth Reduces the Inflammatory Response of Macrophages to Acid Dentine Lysate.International journal of molecular sciences · 2020Article
- Clinical Performance of Short Expandable Dental Implants for Oral Rehabilitation in Highly Atrophic Alveolar Bone: 3-year Results of a Prospective Single-Center Cohort Study.Medicina (Kaunas, Lithuania) · 2020Article
- Ethanol extract ofJournal of International Society of Preventive & Community DentistryArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, culture-independent molecular techniques have been developed to investigate microbiota considered uncultivable. However, the data in the literature suggest that molecular techniques and cultural methods target different spectra of bacteria. The objective of this pilot study was to search for not yet identified oral species in the peri-implant and sub-gingival microbiota in patients without signs of oral pathologies, through the use of the culturomics approach, which has never been used before in dentistry.
methodsFour patients were enrolled; from each patient, samples of sub-gingival and peri-implant plaque were taken and analysed by culturomics.
resultsOf 48 isolated species, only 30 had been previously identified by metagenomics in other studies; on the contrary, 12 species had never been associated with the oral cavity before, and 5 of them had never been isolated from clinical specimens.
conclusionsBy adopting culturomics in dentistry, it could be possible to identify a large amount of fastidious microorganisms that inhabit the oral cavity and to more accurately characterize the microorganisms that lead to periodontitis and peri-implantitis. This evidence could represent an important step forward for the diagnosis and treatment of peri-implantitis, as well as a very useful means for the characterization of new potential aetiologic agents.
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