Evidence map›Paper›PMID 32397584›Full record

ArticleMarine drugs2020

Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation.

Irina M Yermak, Aleksandra V Volod'ko, Eleonora I Khasina, Viktoriya N Davydova, Evgeniy A Chusovitin, Dmitry L Goroshko, Anna O Kravchenko, Tamara F Solov'eva, Victor V Maleev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Irina M YermakG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Aleksandra V Volod'koG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Eleonora I KhasinaFederal Scientific Center of the East Asia Terrestrial Biodiversity, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Viktoriya N DavydovaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Evgeniy A ChusovitinInstitute for Automation and Control Processes, Far Eastern Branch, Russian Academy of Sciences, 5 Radio St., Vladivostok 690041, Russia.
Dmitry L GoroshkoInstitute for Automation and Control Processes, Far Eastern Branch, Russian Academy of Sciences, 5 Radio St., Vladivostok 690041, Russia.
Anna O KravchenkoG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Tamara F Solov'evaG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Prospect 100 let Vladivostoku 159, Vladivostok 690022, Russia.
Victor V MaleevCentral Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare, 3a, Novogireyevskaya St., Moscow 111123, Russia.
Pacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RURussian Academy of Sciences · RUCentral Research Institute of Epidemiology · RUFederal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inhibitory effects of carrageenans (CRGs) on lipopolysaccharide (LPS) induced inflammation in a mouse model of endotoxemia and in complex therapy of patients with enteric infections of Salmonella etiology were studied. The atomic force microscopy (AFM) examination of LPS and its mixture with CRGs showed that the LPS morphology is significantly changed under the action of κ- and κ/β-CRGs. CRGs were able to increase the synthesis of anti-inflammatory interleukin 10 (IL-10) in vitro, and, at low concentrations, their activity in the mixture with LPS was higher. The protective effect of CRGs against

Indexed as

Dietary SupplementsAnimalsCarrageenanDisease Models, AnimalEndotoxemiaEscherichia coli InfectionsHumansLipopolysaccharidesMaleMiceRhodophytaSalmonellaSalmonella Food PoisoningCarrageenanLipopolysaccharidescarrageenancytokinesenteric infectionslipopolysaccharidemacromolecular structurenonspecific resistance to lipopolysaccharidesalmonellosis

Identifiers

PMID32397584
PMCPMC7281451
OpenAlexW3022387703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.