ReviewDiagnostics (Basel, Switzerland)2020
Saliva-Friend and Foe in the COVID-19 Outbreak.
Review in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis.Frontiers in medicine · 2020Pooled it
- Detection of Salivary Small Extracellular Vesicles Associated Inflammatory Cytokines Gene Methylation in Gingivitis.International journal of molecular sciences · 2020Trial
- Wastewater Speaks: Evaluating SARS-CoV-2 Surveillance, Sampling Methods, and Seasonal Infection Trends on a University Campus.Microorganisms · 2025Article
- The effect of novel vitamin D3 compounds on saliva samples from COVID-19 patients: a lab study.Scientific reports · 2024Article
- Submandibular Gland Pathogenesis Following SARS-CoV-2 Infection and Implications for Xerostomia.International journal of molecular sciences · 2024Article
- Saliva-based detection of SARS-CoV-2: a bibliometric analysis of global research.Molecular and cellular biochemistry · 2024Article
- COVID-19 on Oral Health: A New Bilateral Connection for the Pandemic.Biomedicines · 2023Review
- SARS-CoV-2 antigen detection by saliva; an alternative to nasopharyngeal specimen: A cross-sectional study.Health science reports · 2023Article
- RT-LAMP Multicenter Study for SARS-CoV-2 Genome Molecular Detection in Brazilian Swab and Saliva Samples.Diagnostics (Basel, Switzerland) · 2023Article
- Oral Changes in Hospitalized COVID-19 Patients: A Cross-Sectional Multicentric Study.International journal of dentistry · 2023Article
- Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Saliva as a diagnostic specimen for SARS-CoV-2 detection: A scoping review.Oral diseases · 2022Article
- Review
- Salivary gland function, development, and regeneration.Physiological reviews · 2022Review
- Mitigation of SARS-CoV-2 transmission at a large public university.Nature communications · 2022Article
- COVID-19 Diffusion Before Awareness: The Role of Football Match Attendance in Italy.Journal of sports economics · 2022Article
- Saliva as a propitious diagnostic biofluid, biomarker, and bodies first line of defense against COVID-19: A review.Journal of family medicine and primary care · 2022Review
- Investigation of discordant SARS-CoV-2 RT-PCR results using minimally processed saliva.Scientific reports · 2022Article
- Evaluation and Modelling of the Performance of an Automated SARS-CoV-2 Antigen Assay According to Sample Type, Target Population and Epidemic Trends.Diagnostics (Basel, Switzerland) · 2022Article
- A rapid, easy, and scalable whole blood monocyte CD169 assay for outpatient screening during SARS-CoV-2 outbreak, and potentially other emerging disease outbreaks.SAGE open medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The coronavirus disease 2019 (COVID-19) outbreak, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global ongoing pandemic. Timely, accurate and non-invasive SARS-CoV-2 detection in both symptomatic and asymptomatic patients, as well as determination of their immune status, will facilitate effective large-scale pandemic control measures to prevent the spread of COVID-19. Saliva is a biofluid whose anatomical source and location is of particularly strategic relevance to COVID-19 transmission and monitoring. This review focuses on the role of saliva as both a foe (a common mode of viral transmission via salivary droplets and potentially aerosols) and a friend (as a non-invasive diagnostic tool for viral detection and immune status surveillance) in combating COVID-19.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.