Evidence map›Paper›PMID 32397477›Full record

ReviewInternational journal of molecular sciences2020

Recent Advances in Porphyrin-Based Inorganic Nanoparticles for Cancer Treatment.

Hanieh Montaseri, Cherie Ann Kruger, Heidi Abrahamse

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 81 citations in OpenAlex.

  1. Review
  2. Antimicrobial photodynamic therapy withFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Machine learning-based bioactivity prediction of porphyrin derivatives: molecular descriptors, clustering, and model evaluation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  10. Anticancer Activity of Ether Derivatives of Chrysin.Molecules (Basel, Switzerland) · 2025
    Review
  11. Review
  12. Nanotechnology in Infantile Hemangioma Management.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hanieh MontaseriLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein 2028, South Africa.
Cherie Ann KrugerLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein 2028, South Africa.
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein 2028, South Africa.
University of Johannesburg · ZA

Funding

National Research Foundation - South African Research Chairs Initiative 98337
6 · The paper itself

Abstract

The application of porphyrins and their derivatives have been investigated extensively over the past years for phototherapy cancer treatment. Phototherapeutic Porphyrins have the ability to generate high levels of reactive oxygen with a low dark toxicity and these properties have made them robust photosensitizing agents. In recent years, Porphyrins have been combined with various nanomaterials in order to improve their bio-distribution. These combinations allow for nanoparticles to enhance photodynamic therapy (PDT) cancer treatment and adding additional nanotheranostics (photothermal therapy-PTT) as well as enhance photodiagnosis (PDD) to the reaction. This review examines various porphyrin-based inorganic nanoparticles developed for phototherapy nanotheranostic cancer treatment over the last three years (2017 to 2020). Furthermore, current challenges in the development and future perspectives of porphyrin-based nanomedicines for cancer treatment are also highlighted.

Indexed as

PhotochemotherapyTheranostic NanomedicineAnimalsBiocompatible MaterialsCarbonHumansMagnetic Iron Oxide NanoparticlesMammary Neoplasms, ExperimentalMetal NanoparticlesMiceNanoparticlesNeoplasmsPorphyrinsQuantum DotsSilicon DioxideBiocompatible MaterialsCarbonPorphyrinsSilicon Dioxidecancer treatmentinorganic nanoparticlesnanotheranosticsPorphyrins

Identifiers

PMID32397477
PMCPMC7247422
OpenAlexW3023548730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.