ReviewInternational journal of molecular sciences2020
Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Article
- Borylated Five-Membered Ring Iminosugars: Synthesis, Spectroscopic Analysis, and Biological Evaluation for Glycosidase Inhibition and Anticancer Properties for Application in Boron Neutron Capture Therapy (BNCT)-Part 1.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Ethyl (2IUCrData · 2024Article
- Assessing the Potential ofACS pharmacology & translational science · 2024Article
- Harnessing Multistep Chalcogen Bonding Activation in the α-Stereoselective Synthesis of Iminoglycosides.Journal of the American Chemical Society · 2024Article
- Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B.Journal of the American Chemical Society · 2024Article
- Article
- Benefits of Whey Proteins on Type 2 Diabetes Mellitus Parameters and Prevention of Cardiovascular Diseases.Nutrients · 2023Review
- Biocatalytic Cascades toward Iminosugar Scaffolds Reveal Promiscuous Activity of Shikimate Dehydrogenases.ACS central science · 2023Article
- Stereoselective Synthesis of Nojirimycin α-ACS omega · 2022Article
- Tuning the activity of iminosugars: novelJournal of enzyme inhibition and medicinal chemistry · 2021Article
- The Glucocorticoid PYED-1 Disrupts Mature Biofilms ofAntibiotics (Basel, Switzerland) · 2021Article
- Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics.Molecules (Basel, Switzerland) · 2021Article
- The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses.Frontiers in immunology · 2021Article
- Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates ofMarine drugs · 2020Article
- Editorial: Special Issue on "Therapeutic Approaches for Cystic Fibrosis".International journal of molecular sciences · 2020Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Iminosugars are sugar analogues endowed with a high pharmacological potential. The wide range of biological activities exhibited by these glycomimetics associated with their excellent drug profile make them attractive therapeutic candidates for several medical interventions. The ability of iminosugars to act as inhibitors or enhancers of carbohydrate-processing enzymes suggests their potential use as therapeutics for the treatment of cystic fibrosis (CF). Herein we review the most relevant advances in the field, paying attention to both the chemical synthesis of the iminosugars and their biological evaluations, resulting from in vitro and in vivo assays. Starting from the example of the marketed drug NBDNJ (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.