Evidence map›Paper›PMID 32397403›Full record

ArticleNutrients2020

A Nutrigenetic Approach to Investigate the Relationship between Metabolic Traits and Vitamin D Status in an Asian Indian Population.

Buthaina E Alathari, Dhanasekaran Bodhini, Ramamoorthy Jayashri, Nagarajan Lakshmipriya, Coimbatore Subramanian Shanthi Rani, Vasudevan Sudha, Julie A Lovegrove, Ranjit Mohan Anjana, Viswanathan Mohan, Venkatesan Radha and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Buthaina E AlathariHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.
Dhanasekaran BodhiniDepartment of Molecular Genetics, Madras Diabetes Research Foundation, Chennai 603103, India.
Ramamoorthy JayashriDepartment of Biochemistry, Madras Diabetes Research Foundation, Chennai 600086, India.
Nagarajan LakshmipriyaDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai 600086, India.
Coimbatore Subramanian Shanthi RaniDepartment of Clinical Epidemiology, Madras Diabetes Research Foundation, Chennai 600086, India.
Vasudevan SudhaDepartment of Foods, Nutrition and Dietetics Research, Madras Diabetes Research Foundation, Chennai 600086, India.
Julie A LovegroveHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.ORCID 0000-0001-7633-9455
Ranjit Mohan AnjanaDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.
Viswanathan MohanDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.
Venkatesan RadhaDepartment of Molecular Genetics, Madras Diabetes Research Foundation, Chennai 603103, India.
Rajendra PradeepaDepartment of Diabetology, Madras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialities Centre, WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, ICMR Centre for Advanced Research on Diabetes, Gopalapuram, Chennai 600086, India.
Karani S VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK.

Funding

Medical Research Council MR/S024778/1
6 · The paper itself

Abstract

Studies in Asian Indians have examined the association of metabolic traits with vitamin D status. However, findings have been quite inconsistent. Hence, we aimed to explore the relationship between metabolic traits and 25-hydroxyvitamin D [25(OH)D] concentrations. We investigate whether this relationship was modified by lifestyle factors using a nutrigenetic approach in 545 Asian Indians randomly selected from the Chennai Urban Rural Epidemiology Study (219 normal glucose tolerant individuals, 151 with pre-diabetes and 175 individuals with type 2 diabetes). A metabolic genetic risk score (GRS) was developed using five common metabolic disease-related genetic variants. There was a significant interaction between metabolic GRS and carbohydrate intake (energy%) on 25(OH)D (P

Indexed as

NutrigenomicsAdultAgedAged, 80 and overAllelesAsian PeopleBody CompositionBody ConstitutionDiabetes Mellitus, Type 2Dietary CarbohydratesDiet, Carbohydrate-RestrictedEatingExerciseFemaleGenetic VariationHumans25-hydroxyvitamin DDietary CarbohydratesVitamin D25(OH)DAsian Indiancarbohydrate intakeCURESGRSmetabolic traitsSNPvitamin D

Identifiers

PMID32397403
PMCPMC7285077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.