Evidence map›Paper›PMID 32397205›Full record

ArticleAntibiotics (Basel, Switzerland)2020

PYED-1 Inhibits Biofilm Formation and Disrupts the Preformed Biofilm of

Adriana Vollaro, Anna Esposito, Eliana Pia Esposito, Raffaele Zarrilli, Annalisa Guaragna, Eliana De Gregorio

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. mSystems · 2024
    Article
  5. Assessing the Potential ofACS pharmacology & translational science · 2024
    Article
  6. Article
  7. Article
  8. PYED-1 Overcomes Colistin Resistance inPathogens (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Restoring Ampicillin Sensitivity in Multidrug-ResistantJournal of microbiology and biotechnology · 2023
    Article
  11. Article
  12. Antimicrobial Activity of Some Steroidal Hydrazones.Molecules (Basel, Switzerland) · 2023
    Article
  13. Article
  14. The Glucocorticoid PYED-1 Disrupts Mature Biofilms ofAntibiotics (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Antibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Adriana VollaroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
Anna EspositoDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Eliana Pia EspositoDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Raffaele ZarrilliDepartment of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Annalisa GuaragnaDepartment of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.
Eliana De GregorioDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.
University of Naples Federico II · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN2017 (Grant 2017SFBFER to RZ)
6 · The paper itself

Abstract

Pregnadiene-11-hydroxy-16α,17α-epoxy-3,20-dione-1 (PYED-1), a heterocyclic corticosteroid derivative of deflazacort, exhibits broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria. Here, we investigated the effect of PYED-1 on the biofilms of

Indexed as

antibiofilm activitybiofilm eradication agentbiofilm formationcorticosteroidpreformed biofilmStaphylococcus aureus

Identifiers

PMID32397205
PMCPMC7277567
OpenAlexW3023075643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.