Evidence map›Paper›PMID 32397196›Full record

ReviewBiomolecules2020

Nanotechnology-Based Strategies to Develop New Anticancer Therapies.

Massimiliano Magro, Andrea Venerando, Alberto Macone, Gianluca Canettieri, Enzo Agostinelli, Fabio Vianello

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Unlocking the Potential ofPharmaceutics · 2025
    Review
  3. The effect of biosynthesized zinc oxide nanoparticles on gene expression and apoptosis in triple-negative breast cancer cells.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. FeInternational journal of nanomedicine · 2024
    Article
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  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Massimiliano MagroDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
Andrea VenerandoDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
Alberto MaconeDepartment of Biochemical Sciences, A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Gianluca CanettieriPasteur Laboratory, Department of Molecular Medicine, Sapienza University of Rome, I-00161 Rome, Italy.
Enzo AgostinelliDepartment of Biochemical Sciences, A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Fabio VianelloDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
University of Padua · ITInternational Flame Research Foundation · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blooming of nanotechnology has made available a limitless landscape of solutions responding to crucial issues in many fields and, nowadays, a wide choice of nanotechnology-based strategies can be adopted to circumvent the limitations of conventional therapies for cancer. Herein, the current stage of nanotechnological applications for cancer management is summarized encompassing the core nanomaterials as well as the available chemical-physical approaches for their surface functionalization and drug ligands as possible therapeutic agents. The use of nanomaterials as vehicles to delivery various therapeutic substances is reported emphasizing advantages, such as the high drug loading, the enhancement of the pay-load half-life and bioavailability. Particular attention was dedicated to highlight the importance of nanomaterial intrinsic features. Indeed, the ability of combining the properties of the transported drug with the ones of the nano-sized carrier can lead to multifunctional theranostic tools. In this view, fluorescence of carbon quantum dots, optical properties of gold nanoparticle and superparamagnetism of iron oxide nanoparticles, are fundamental examples. Furthermore, smart anticancer devices can be developed by conjugating enzymes to nanoparticles, as in the case of bovine serum amine oxidase (BSAO) and gold nanoparticles. The present review is aimed at providing an overall vision on nanotechnological strategies to face the threat of human cancer, comprising opportunities and challenges.

Indexed as

AdsorptionAnimalsAntineoplastic AgentsBiomedical TechnologyHumansNanoparticlesNanotechnologyAntineoplastic Agentsamino oxidasesbiomoleculescancerhyperthermiananoparticlespolyamines

Identifiers

PMID32397196
PMCPMC7278173
OpenAlexW3023724473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.