Evidence map›Paper›PMID 32397169›Full record

ArticleCells2020

RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment.

Alvaro Torres-Gomez, Jose Luis Sanchez-Trincado, Víctor Toribio, Raul Torres-Ruiz, Sandra Rodríguez-Perales, María Yáñez-Mó, Pedro A Reche, Carlos Cabañas, Esther M Lafuente

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Targeting integrin pathways: mechanisms and advances in therapy.Signal transduction and targeted therapy · 2023
    Review
  7. Article
  8. Review
  9. Expression of the phagocytic receptors αFrontiers in immunology · 2022
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Alvaro Torres-GomezDepartment of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, and Instituto (I+12), 28040 Madrid, Spain.ORCID 0000-0002-7377-1581
Jose Luis Sanchez-TrincadoDepartment of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, and Instituto (I+12), 28040 Madrid, Spain.
Víctor ToribioSevero Ochoa Center for Molecular Biology (CSIC-UAM), 28049 Madrid, Spain.
Raul Torres-RuizMolecular Cytogenetics and Genome Editing Unit, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain.
Sandra Rodríguez-PeralesMolecular Cytogenetics and Genome Editing Unit, Human Cancer Genetics Program, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain.
María Yáñez-MóSevero Ochoa Center for Molecular Biology (CSIC-UAM), 28049 Madrid, Spain.ORCID 0000-0001-7484-2866
Pedro A RecheDepartment of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, and Instituto (I+12), 28040 Madrid, Spain.
Carlos CabañasDepartment of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, and Instituto (I+12), 28040 Madrid, Spain.ORCID 0000-0002-8767-060X
Esther M LafuenteDepartment of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, and Instituto (I+12), 28040 Madrid, Spain.ORCID 0000-0001-8466-1022
Universidad Complutense de Madrid · ESHospital Universitario de La Princesa · ESJosep Carreras Leukaemia Research Institute · ESSpanish National Cancer Research Centre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phagocytic integrins and complement receptors α

Indexed as

PhagocytosisSignal TransductionActinsAdaptor Proteins, Signal TransducingCell Adhesion MoleculesCell MembraneComplement System ProteinsGene Knockdown TechniquesHL-60 CellsHumansIntegrinsManganeseMembrane ProteinsMicrofilament ProteinsPhosphoproteinsPhosphorylationActinsAdaptor Proteins, Signal TransducingAPBB1IP protein, humanCell Adhesion MoleculesComplement System ProteinsIntegrinsManganeseMembrane ProteinsMicrofilament ProteinsPhosphoproteinsReceptors, ComplementVasodilator-Stimulated PhosphoproteincomplementCR3CR4Mac-1outside-inphagocytosisRIAMVASPβ2 integrins

Identifiers

PMID32397169
PMCPMC7291270
OpenAlexW3023929055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.