ArticleJournal of child psychology and psychiatry, and allied disciplines2021
Diagnostic classification of irritability and oppositionality in youth: a global field study comparing ICD-11 with ICD-10 and DSM-5.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Irritability as a Transdiagnostic Construct Across Childhood and Adolescence: A Systematic Review and Meta-analysis.Clinical child and family psychology review · 2025Pooled it
- Parent training for the treatment of irritability in children and adolescents: a multisite randomized controlled, 3-parallel-group, evaluator-blinded, superiority trial.BMC psychology · 2022Trial
- Integrating Screens and Spoons: An Exploratory Study on Digital Technology's Influence on Parent-Child Interactions.European journal of investigation in health, psychology and education · 2025Article
- Treatment adherence, therapeutic alliance, and clinical outcomes during an exposure-based cognitive-behavioral therapy for pediatric irritability.BMC psychiatry · 2025Observational
- Scientific validation of the ICD-11 CDDR.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Article
- Trajectories of oppositional defiant disorder severity from adolescence to young adulthood and substance use, mental health, and behavioral problems.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2023Article
- Discussant: Distilling symptom heterogeneity in youth with ODD: a commentary on Leadbeater et al., 2023.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2023Article
- New research on validity and clinical utility of ICD-11 vs. ICD-10 and DSM-5 diagnostic categories.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Improving Our Understanding of Impaired Social Problem-Solving in Children and Adolescents with Conduct Problems: Implications for Cognitive Behavioral Therapy.Clinical child and family psychology review · 2022Review
- Associations Between Chronic Irritability and Sensory Processing Difficulties in Children and Adolescents.Frontiers in psychiatry · 2022Article
- Worldwide initiatives aimed to train professionals in the use of the ICD-11.Annals of general psychiatry · 2021Article
- ICD-11-related educational activities.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- Taxonomy and utility in the diagnostic classification of mental disorders.Journal of clinical psychology · 2021Article
- An organization- and category-level comparison of diagnostic requirements for mental disorders in ICD-11 and DSM-5.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
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Authors and funding
21 authors at 16 institutions in 8 countries.
Funding
Abstract
backgroundSevere irritability has become an important topic in child and adolescent mental health. Based on the available evidence and on public health considerations, WHO classified chronic irritability within oppositional defiant disorder (ODD) in ICD-11, a solution markedly different from DSM-5's (i.e. the new childhood mood diagnosis, disruptive mood dysregulation disorder [DMDD]) and from ICD-10's (i.e. ODD as one of several conduct disorders without attention to irritability). In this study, we tested the accuracy with which a global, multilingual, multidisciplinary sample of clinicians were able to use the ICD-11 classification of chronic irritability and oppositionality as compared to the ICD-10 and DSM-5 approaches.
methodsClinicians (N = 196) from 48 countries participated in an Internet-based field study in English, Spanish, or Japanese and were randomized to review and use one of the three diagnostic systems. Through experimental manipulation of validated clinical vignettes, we evaluated how well clinicians in each condition could identify chronic irritability versus nonirritable oppositionality, episodic bipolar disorder, dysthymic depression, and normative irritability.
resultsCompared to ICD-10 and DSM-5, ICD-11 led to more accurate identification of severe irritability and better differentiation from boundary presentations. Participants using DSM-5 largely failed to apply the DMDD diagnosis when it was appropriate, and they more often applied psychopathological diagnoses to developmentally normative irritability.
conclusionsThe formulation of irritability and oppositionality put forth in ICD-11 shows evidence of clinical utility, supporting accurate diagnosis. Global mental health clinicians can readily identify ODD both with and without chronic irritability.
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