Evidence map›Paper›PMID 32396327›Full record

ArticleACS chemical biology2020

Potential G-Quadruplex Forming Sequences and

Manuel Jara-Espejo, Aaron M Fleming, Cynthia J Burrows

Open access · bronzeAbstract read
In one paragraph

Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Comprehensive analysis and validation of mBMC veterinary research · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Epigenetic control of skeletal muscle atrophy.Cellular & molecular biology letters · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Crosstalk between G-quadruplex and ROS.Cell death & disease · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Manuel Jara-EspejoDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0002-5454-7787
Aaron M FlemingDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0002-2000-0310
Cynthia J BurrowsDepartment of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, United States.ORCID 0000-0001-7253-8529
University of Utah · USUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Nanopore Detection of DNA DamageR01GM093099 · NIGMS · UNIVERSITY OF UTAH · PI BURROWS, CYNTHIA J · 2011 to 2021
$3.0M
NIGMS NIH HHS R01 GM093099
6 · The paper itself

Abstract

Maturation of mRNA in humans involves modifying the 5' and 3' ends, splicing introns, and installing epitranscriptomic modifications that are essential for mRNA biogenesis. With respect to epitranscriptomic modifications, they are usually installed in specific consensus motifs, although not all sequences are modified suggesting a secondary structural component to site selection. Using bioinformatic analysis of published data, we identify in human mature-mRNA that potential RNA G-quadruplex (rG4) sequences colocalize with the epitranscriptomic modifications

Indexed as

G-QuadruplexesIntronsRNA Splice SitesAdenosineHumansPseudouridineRNA PrecursorsRNA SplicingTranscriptomeAdenosineN-methyladenosinePseudouridineRNA PrecursorsRNA Splice Sites

Identifiers

PMID32396327
PMCPMC7309266
OpenAlexW3024910023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.