Evidence map›Paper›PMID 32396199›Full record

ArticleGigaScience2020

Community standards for open cell migration data.

Alejandra N Gonzalez-Beltran, Paola Masuzzo, Christophe Ampe, Gert-Jan Bakker, Sébastien Besson, Robert H Eibl, Peter Friedl, Matthias Gunzer, Mark Kittisopikul, Sylvia E Le Dévédec and 15 more

Abstract read
In one paragraph

Article in GigaScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Systematic data analysis pipeline for quantitative morphological cell phenotyping.Computational and structural biotechnology journal · 2024
    Review
  6. Methods and computational tools to study eukaryotic cell migrationFrontiers in cell and developmental biology · 2024
    Review
  7. Article
  8. Review
  9. Liquid biopsy and glioblastoma.Exploration of targeted anti-tumor therapy · 2023
    Review
  10. Article
  11. Liquid biopsy for monitoring medulloblastoma.Extracellular vesicles and circulating nucleic acids · 2022
    Review
  12. Cell-free DNA as a biomarker in cancer.Extracellular vesicles and circulating nucleic acids · 2022
    Review
  13. Article
  14. Review
  15. Data science in cell imaging.Journal of cell science · 2021
    Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Alejandra N Gonzalez-BeltranOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford OX1 3QG, Oxford, UK.
Paola MasuzzoVIB-UGent Center for Medical Biotechnology, VIB, A. Baertsoenkaai 3, B-9000, Ghent, Belgium.
Christophe AmpeDepartment of Biomolecular Medicine, Ghent University, A. Baertsoenkaai 3, B-9000, Ghent, Belgium.
Gert-Jan BakkerDepartment of Cell Biology, Radboud Institute for Molecular Life Sciences, Geert Grooteplein 28 6525 GA Nijmegen, The Netherlands.
Sébastien BessonCentre for Gene Regulation & Expression & Division of Computational Biology, University of Dundee, School of Life Sciences, Dow St Dundee DD1 5EH, Scotland, UK.
Robert H EiblGerman Cancer Research Center, DKFZ Alumni Association, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Peter FriedlDepartment of Cell Biology, Radboud Institute for Molecular Life Sciences, Geert Grooteplein 28 6525 GA Nijmegen, The Netherlands.
Matthias GunzerInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-Essen, Universitätsstr. 2, 45141 Essen, Germany.
Mark KittisopikulDepartment of Biophysics, UT Southwestern Medical Center, 5323 Harry Hines Blvd. Dallas, TX 75390, USA.
Sylvia E Le DévédecDivision of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, PO box 9502 2300 RA Leiden, The Netherlands.
Simone LeoCentre for Gene Regulation & Expression & Division of Computational Biology, University of Dundee, School of Life Sciences, Dow St Dundee DD1 5EH, Scotland, UK.
Josh MooreCentre for Gene Regulation & Expression & Division of Computational Biology, University of Dundee, School of Life Sciences, Dow St Dundee DD1 5EH, Scotland, UK.
Yael ParanIDEA Bio-Medical Ltd, 2 Prof. Bergman St., Rehovot 76705, Israel.
Jaime PriluskyLife Science Core Facilities, Weizmann Institute of Science, P.O. Box 26 Rehovot 76100, Israel.
Philippe Rocca-SerraOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford OX1 3QG, Oxford, UK.
Philippe RoudotLyda Hill Department of Bioinformatics, UT Southwestern Medical Center, 5323 Harry Hines Blvd. Dallas, TX 75390, USA.
Marc SchusterInstitute for Experimental Immunology and Imaging, University Hospital, University Duisburg-Essen, Universitätsstr. 2, 45141 Essen, Germany.
Gwendolien SergeantDepartment of Biomolecular Medicine, Ghent University, A. Baertsoenkaai 3, B-9000, Ghent, Belgium.
Staffan StrömbladDepartment of Biosciences and Nutrition, Karolinska Institutet, Neo, SE-141 83 Huddinge, Sweden.
Jason R SwedlowCentre for Gene Regulation & Expression & Division of Computational Biology, University of Dundee, School of Life Sciences, Dow St Dundee DD1 5EH, Scotland, UK.
Merijn van ErpDepartment of Cell Biology, Radboud Institute for Molecular Life Sciences, Geert Grooteplein 28 6525 GA Nijmegen, The Netherlands.
Marleen Van TroysDepartment of Biomolecular Medicine, Ghent University, A. Baertsoenkaai 3, B-9000, Ghent, Belgium.
Assaf ZaritskyDepartment of Software and Information Systems Engineering, Ben-Gurion University of the Negev, P.O.B. 653, 8410501 Beer-Sheva, Israel.
Susanna-Assunta SansoneOxford e-Research Centre, Department of Engineering Science, University of Oxford, 7 Keble Road, Oxford OX1 3QG, Oxford, UK.
Lennart MartensVIB-UGent Center for Medical Biotechnology, VIB, A. Baertsoenkaai 3, B-9000, Ghent, Belgium.

Funding

Biotechnology and Biological Sciences Research Council BB/E025080/1Biotechnology and Biological Sciences Research Council BB/I000771/1European Research Council 617430
6 · The paper itself

Abstract

Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration.

Indexed as

BiomarkersCell MovementComputational BiologyData AnalysisDatabases, FactualMetadataResearchBiomarkersbiotrackscell migrationCMSOdata standardsFAIR datafrictionless data packagemetadataMIACME

Identifiers

PMID32396199
PMCPMC7317087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.