Evidence map›Paper›PMID 32395842›Full record

ArticleJournal of advanced nursing2020

Effectiveness of a hydrophobic dressing for microorganisms' colonization of vascular ulcers: Protocol for a randomized controlled trial (CUCO-UV Study).

Juan C Morilla-Herrera, José M Morales-Asencio, Alberto J Gómez-González, Antonio Díez-De Los Ríos, Inmaculada Lupiáñez-Pérez, Carlos Acosta-Andrade, Marta Aranda-Gallardo, Ana B Moya-Suárez, Shakira Kaknani-Uttumchandani, Silvia García-Mayor

Open access · hybridAbstract read
In one paragraph

Article in Journal of advanced nursing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Juan C Morilla-HerreraDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.
José M Morales-AsencioDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.ORCID https://orcid.org/0000-0001-7911-7487
Alberto J Gómez-GonzálezDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.ORCID https://orcid.org/0000-0002-9560-7213
Antonio Díez-De Los RíosDistrito Sanitario Málaga - Valle del Guadalhorce, Malaga, Spain.
Inmaculada Lupiáñez-PérezDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.
Carlos Acosta-AndradeDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.
Marta Aranda-GallardoInstituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain.ORCID https://orcid.org/0000-0003-0399-9561
Ana B Moya-SuárezInstituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain.
Shakira Kaknani-UttumchandaniDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.
Silvia García-MayorDepartment of Nursing, University of Málaga, Faculty of Health Sciences, Malaga, Spain.ORCID https://orcid.org/0000-0002-3913-3850
Instituto de Investigación Biomédica de Málaga · ESAgencia Sanitaria Costa del Sol · ESUniversidad de Málaga · ES

Funding

BSN Medical
6 · The paper itself

Abstract

aimTo determine the effectiveness of a hydrophobic dressing (Cutimed Sorbact

designOpen randomized controlled trial, with blinded endpoint.

methodsPatients with chronic venous leg ulcers with signs of critical colonization will be randomized in a concealed sequence using computer software to receive one of the alternative dressings. A total of 204 participants recruited in Primary Health Care and nursing homes will be necessary to assure statistical power. Measures will include sociodemographic variables, wound-related variables (area, exudate, and time to healing), level of pain, adverse effects, and health-related quality of life. Smear samples will be collected from the ulcers and will be subject to DNA-typing technique through polymerase chain reaction to obtain the level of colony-forming units. Measures will be collected at baseline, 4, 8, and 12 weeks. DISCUSSION: Elevated levels of microorganisms prevent wound healing and favour its chronification. The main target when colonization is present is to reduce the bacterial load to levels that promote immune system mobilization. Hydrophobic dressings prevent the formation of biofilm in the wound by means of physical effect, so that the possibility of antimicrobial resistance is significantly reduced. IMPACT: Current evidence about the effectiveness of dressings to minimize venous leg ulcers colonization is very limited. Previous studies have important methodological flaws. This study will permit to obtain the effectiveness of hydrophobic dressings against silver dressings with a robust design based on conditions of routine clinical practice in Primary Health Care and nursing homes.

Indexed as

bacterial adhesionbacterial loadleg injuriesnursingvaricose ulcerwound infections

Identifiers

PMID32395842
PMCPMC7496185
OpenAlexW3025622030

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.