ArticleGynecologic oncology reports2020
A case of multi-agent drug resistant choriocarcinoma treated with Pembrolizumab.
Article in Gynecologic oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Pembrolizumab in gestational trophoblastic neoplasia: Systematic review and meta-analysis with sub-group analysis of potential prognostic factors.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- Immunotherapy in the treatment of chemoresistant gestational trophoblastic neoplasia - systematic review with a presentation of the first 4 Brazilian cases.Clinics (Sao Paulo, Brazil) · 2023Pooled it
- A Rare Case of Primary Pulmonary Choriocarcinoma Metastasizing to the Kidney: Diagnostic and Therapeutic Complexities.Cancer reports (Hoboken, N.J.) · 2026Article
- Checkpoint Inhibition in Gestational Trophoblastic Neoplasia: A Narrative Review on the Reawakening of Antitumor Immunity.Advances in therapy · 2026Review
- Use of a PD-1 checkpoint inhibitor in a patient with ultra-high-risk gestational trophoblastic neoplasia and gastrointestinal metastases.Gynecologic oncology reports · 2024Article
- Chemo-resistant Gestational Trophoblastic Neoplasia and the Use of Immunotherapy: A Case Report and Review of Literature.Acta medica Philippina · 2024Article
- Immunotherapy for Gestational Trophoblastic Neoplasia: A New Paradigm.Gynecologic and obstetric investigation · 2024Review
- A poor prognostic male choriocarcinoma with multiple systemic metastases: a case report and the literature review.Frontiers in medicine · 2024Article
- Case report: Molecular profiling facilitates the diagnosis of a challenging case of lung cancer with choriocarcinoma features.Frontiers in oncology · 2024Article
- Primary hepatic metastatic epitheloid trophoblastic tumor of the uterus treated with multimodal therapy including pembrolizumab and thermoablation. Case report of an extremely rare disease and review of the literature.Gynecologic oncology reports · 2023Article
- Combined chemotherapy and pembrolizumab salvages multi-chemotherapy agent and avelumab resistant choriocarcinoma: A case report.Gynecologic oncology reports · 2023Article
- Anti-PD-1 therapy plus chemotherapy versus anti-PD-1 therapy alone in patients with high-risk chemorefractory or relapsed gestational trophoblastic neoplasia: a multicenter, retrospective study.EClinicalMedicine · 2023Article
- Postmenopausal mixed gestational trophoblastic neoplasia with complete response to immunotherapy - A case report.Gynecologic oncology reports · 2023Article
- Immune checkpoint inhibitor using in cases with gestational trophoblastic diseases.Medical oncology (Northwood, London, England) · 2023Review
- Subarachnoid hemorrhage in a postpartum mother: A rare manifestation of an uncommon disease.Gynecologic oncology reports · 2022Article
- Case Report: Treatment of primary pulmonary choriocarcinoma with lung lobectomy and adjuvant chemotherapy.Gynecologic oncology reports · 2022Article
- PD-L1 in gestational trophoblastic disease: an antibody evaluation.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Review
- Non-gestational choriocarcinoma with hyperprogression on pembrolizumab: A case report and review of the literature.Gynecologic oncology reports · 2022Article
- Effectiveness and Safety of Toripalimab Combination Therapies for Patients With Chemo-Resistant Choriocarcinoma.Frontiers in oncology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
•High-risk multi-agent drug resistant GTN is a life threatening disease.•Majority of choriocarcinomas show intense PD-L1 immunoreactivity.•Pembrolizumab increases antitumor activity.•Effectiveness of Pembrolizumab in treating patients with high-risk multi-agent drug resistant GTN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.