ReviewBone reports2020
A review of the latest insights into the mechanism of action of strontium in bone.
Review in Bone reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it, 189 citations in OpenAlex.
- Effectiveness of strontium/silver-based titanium surface coatings in improving antibacterial and osteogenic implant characteristics: a systematic review ofFrontiers in bioengineering and biotechnology · 2024Pooled it
- Spatiotemporally programming the immune-osteogenic cascade with a dual-immunomodulatory scaffold for functional bone regeneration.Bioactive materials · 2026Article
- Multi-staged mineralization and biomarker preservation in a 113-million-year-old pterosaur bone via redox shifts in diagenesis.iScience · 2026Article
- Research Progress and Translational Perspectives of Piezoelectric Materials in Dental Implant Surface Engineering.Journal of functional biomaterials · 2026Review
- Osteogenic Potential of a Three-Phase Strontium- and Silicon-Doped Tricalcium Silicate Cement on Dental Pulp Stem Cells: An In Vitro Study.Clinical and experimental dental research · 2026Article
- A Multifunctional Therapeutic Platform: Ce/Zn/Sr-Doped Mesoporous Bioactive Glass Nanoparticles for Bone Repair.International journal of molecular sciences · 2026Article
- Deciphering the Cellular Effects of Strontium Chloride and Potassium Carbonate on Induced Pluripotent Stem Cells and Their Derivative Cardiomyocytes.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Evaluation of an angio-osseo inductive bone ceramic versus demineralised freeze-dried bone allograft in the treatment of periodontal intrabony defects: a randomised controlled clinical trial.Biomaterial investigations in dentistry · 2026Article
- Antiosteolytic Bisphosphonate Metallodrug Coordination Networks: Dissolution Profiles andACS applied bio materials · 2025Article
- SrO-Containing Bioactive Glasses in the SiOACS biomaterials science & engineering · 2025Review
- Enhancing Radiopacity and Antibacterial Activity of Osteogenic Calcium Silicate Cement by Incorporating Strontium.Journal of functional biomaterials · 2025Article
- The Effect of Strain Rate on Bone Fragility and Clinical Applications.Bioengineering (Basel, Switzerland) · 2025Article
- Biodegradable Zn-0.8Mg-0.2Sr alloy as an internal fixation material exhibits controlled degradation with enhanced osteogenesis.RSC advances · 2025Article
- From hard tissues to beyond: Progress and challenges of strontium-containing biomaterials in regenerative medicine applications.Bioactive materials · 2025Review
- Strontium-Substituted Calcium Orthophosphates: Structure, Stability, Morphology, and Biomedical Applications.International journal of molecular sciences · 2025Review
- Article
- 3D-Printed Cell-Instructive Scaffolds Based onACS biomaterials science & engineering · 2025Article
- Dual Antibacterial and Soft-Tissue-Integrative Effect of Combined Strontium Acetate and Silver Nitrate on Peri-Implant Environment: Insights from Multispecies Biofilms and a 3D Coculture Model.ACS applied materials & interfaces · 2025Article
- Exploring the role of strontium-based nanoparticles in modulating bone regeneration and antimicrobial resistance: a public health perspective.RSC advances · 2025Review
- Sustained release of Sr and Ca from a micronanotopographic titanium surface improves osteoblast function.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interest in strontium (Sr) has persisted over the last three decades due to its unique mechanism of action: it simultaneously promotes osteoblast function and inhibits osteoclast function. While this mechanism of action is strongly supported by
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.