ArticleAnnals of translational medicine2020
Risk factors for uroseptic shock in hospitalized patients aged over 80 years with urinary tract infection.
Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Trends and disparities in urinary tract infections-related mortality in the United States from 1999 to 2023: Insights from CDC WONDER.Medicine · 2026Article
- Comorbidities, Routine Biomarkers and Early Septic Shock Occurrence in Patients with Sepsis: A Retrospective Longitudinal Study.Diagnostics (Basel, Switzerland) · 2026Article
- The relationship between urinary tract infections and sepsis: results from Mendelian randomization and MIMIC data study.World journal of urology · 2026Article
- Risk Factors and Development of a Predictive Model for In-Hospital Mortality in Hemodynamically Stable Older Adults with Urinary Tract Infection.Medicina (Kaunas, Lithuania) · 2025Article
- Recurrent Urosepsis Following Stent Removal for Ureteral Stones: A Case Report.Case reports in urology · 2025Article
- Intestinal microbiology and urinary tract infection associated risk in long-term aged care residents.Communications medicine · 2024Article
- Comprehensive insights into UTIs: from pathophysiology to precision diagnosis and management.Frontiers in cellular and infection microbiology · 2024Review
- Risk Factors for Bacteremia and Its Clinical Impact on Complicated Community-Acquired Urinary Tract Infection.Microorganisms · 2023Article
- Predictors of Urosepsis Post Percutaneous Nephrolithotomy at King Abdulaziz Medical City, Riyadh.Cureus · 2023Article
- Clinical characteristics and prognosis in patients with urosepsis from intensive care unit in Shanghai, China: a retrospective bi-centre study.BMC anesthesiology · 2021Article
- Trends in Incidence and Outcomes of Hospitalizations for Urinary Tract Infection among Older People in Spain (2001-2018).Journal of clinical medicine · 2021Article
- Multidrug-Resistant Bacterial Infections in Geriatric Hospitalized Patients before and after the COVID-19 Outbreak: Results from a Retrospective Observational Study in Two Geriatric Wards.Antibiotics (Basel, Switzerland) · 2021Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to compare clinical characteristics and outcomes in individuals of different age groups with urinary tract infection (UTI), and to identify the relationships among advanced age and uroseptic shock.
methodsThis retrospective study compared clinical characteristics and outcomes in patients in different age groups with UTI and identified relationships between advanced age and uroseptic shock among hospitalized patients with UTI in an acute hospital care setting from January 2006 to October 2018. Patients were divided into young (age below 65 years), old (65-80 years), and very old (above 80 years) groups.
resultsOf 1,043 participants, 269 (25.8%) were very old and 200 (19.2%) developed uroseptic shock. Very old age [odds ratio (OR) 1.99, 95% confidence interval (CI): 1.25-3.19, P=0.004], male (OR 1.54, 95% CI: 1.07-2.24, P=0.022), presented flank pain (OR 1.54, 95% CI: 1.05-2.24, P=0.025), congestive heart failure (CHF) (OR 2.54, 95% CI: 1.27-5.06, P=0.008), acute kidney injury (AKI) (OR 4.19, 95% CI: 2.78-6.30, P<0.001), bacteremia (OR 1.78, 95% CI: 1.25-2.53, P=0.001), and multiple drug-resistant (MDR) bacteria (OR 1.43, 95% CI: 1.02-2.00, P=0.039) were associated with an increased risk of uroseptic shock in patients with UTI. In very old patients with UTI, bacteremia (OR 2.54, 95% CI: 1.38-4.69, P=0.003) and AKI (OR 4.37, 95% CI: 2.15-8.90, P<0.001) were independently associated with uroseptic shock.
conclusionsVery old patients with UTI had a higher risk of developing uroseptic shock than younger patients. Bacteremia was an independent risk factor for uroseptic shock in very old patients with UTI.
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