Evidence map›Paper›PMID 32395341›Full record

ArticleTuberculosis research and treatment2020

Tuberculosis among Patients Undergoing Solid Organ Transplantation or Dialysis in a Low-Endemic Country, 2004-2017.

Marie Helleberg, Daniel Cho, Christina Ekenberg, Søren Sørensen, Marianne Rix, Finn Gustafsson, Allan Rasmussen, Michael Perch, Peter H S Andersen, Jens D Lundgren and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Tuberculosis research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marie HellebergDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.ORCID https://orcid.org/0000-0002-2370-1657
Daniel ChoCentre of Excellence for Health, Immunity and Infections (CHIP), Copenhagen University Hospital/Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Christina EkenbergCentre of Excellence for Health, Immunity and Infections (CHIP), Copenhagen University Hospital/Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Søren SørensenDepartment of Nephrology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Marianne RixDepartment of Nephrology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Finn GustafssonDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Allan RasmussenDepartment of Surgery C, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Michael PerchDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Peter H S AndersenDepartment of Infection Epidemiology and Prevention, The State Serum Institute, Artillerivej 5, 2300 Copenhagen S, Denmark.
Jens D LundgrenDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.
Aase Bengaard AndersenDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ö, Denmark.ORCID https://orcid.org/0000-0003-4779-7603
Copenhagen University Hospital · DKStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk of active TB among solid organ transplant (SOT) recipients and patients initiating chronic dialysis in a country with low incidence of TB is not well elucidated.

methodsPatients aged >18 years who were transplanted with a solid organ or initiated chronic dialysis at Copenhagen University Hospital in the period 2004-2017 were followed from date of transplantation or initiation of dialysis. Data on demographics and outcomes were obtained from nationwide registries.

resultsWe included 1,989 SOT recipients and 1,305 patients initiating chronic dialysis, who were followed for a total of 9,785 and 4,196 person-years (PY), respectively. Only a minority of patients had been screened for latent TB prior to SOT or initiation of dialysis. The incidence rates (IRs)/100,000 PY of TB among patients from medium/high TB endemic areas were 358 (95% CI 115-1,110) and 1,266 (95% CI 681-2354) for SOT and dialysis patients, respectively, whereas IRs among patients of Danish origin were 11 (95% CI 2-81) and 31 (95% CI 4-218).

conclusionThe incidence of TB among immunosuppressed immigrants from medium/high TB endemic countries was very high, while the risk of TB among patients from low-endemic countries was minimal.

Identifiers

PMID32395341
PMCPMC7201514
OpenAlexW3019675719

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.