ArticleJournal of thoracic disease2020
Minimally invasive surgery for left ventricular assist device implantation is safe and associated with a decreased risk of right ventricular failure.
Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- The association of vasoactive-inotropic score and surgical patients' outcomes: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Vaso-active inotropic scores: Clinical value, pros and cons.JHLT open · 2026Article
- Minimally invasive LVAD implantation for advanced heart failure: a single-center retrospective analysis and the promise of minimally invasive approaches.Journal of cardiothoracic surgery · 2025Article
- Prediction of Right Heart Failure After Left Ventricular Assist Device: Opening Pandora's Box.Reviews in cardiovascular medicine · 2025Review
- Echocardiographic predictors of right ventricular failure following left ventricular assist device implantation: Systematic review and meta-analysis.Global cardiology science & practice · 2025Article
- Flow dynamics during the HeartWare HVAD to HeartMate 3 exchange: A computational study assessing differential graft lengths and surgical techniques.JTCVS techniques · 2022Article
- Prediction, prevention, and management of right ventricular failure after left ventricular assist device implantation: A comprehensive review.Frontiers in cardiovascular medicine · 2022Review
- Commentary: Less-invasive approaches to big complex problems in patients with end-stage heart disease.JTCVS techniques · 2020Article
- Preoperative risk factors of early right ventricular failure-following left ventricular assist device implantation.Journal of thoracic disease · 2020Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRight ventricular failure (RVF) after left ventricular assist device (LVAD) implantation is associated with significant mortality and morbidity. The objective of this study was to determine pre- and postoperative risk factors associated with the occurrence of RVF after LVAD implantation.
methodsThis retrospective study included 68 patients who received LVADs between 2010 and 2018 either for bridge to transplant (40 patients, 58.8%) or bridge to destination therapy (28 patients, 41.2%). RVF after LVAD implantation was defined according to the INTERMACS classification. The primary endpoint was the occurrence of RVF. The secondary endpoints were hospital mortality and morbidity and long-term survival.
resultsThe majority of patients (61.8%) had an INTERMACS profile 1 (36.8%) or 2 (25.0%). The LVAD was implanted either by sternotomy (37 patients, 54.4%) or thoracotomy (31 patients, 45.6%). RVF after LVAD implantation was observed in 32 patients (47.1%). In univariate analysis, an elevated serum glutamic oxaloacetic transaminase (SGOT) (P=0.028) and a high preoperative vasoactive inotropic score (VIS) (P=0.028) were significantly associated with an increased risk of RVF, whereas the implantation of LVAD through a thoracotomy approach was associated with a significant reduction in this risk (P=0.006). The multivariate analysis demonstrated that only the thoracotomy approach was significantly associated with decreased risk of RVF (odds ratio =0.33, 95% confidence interval: 0.17-0.96; P=0.042). Hospital mortality was 53.1% and 5.6% in the RVF and control groups, respectively (P<0.0001). The incidence of stroke and postoperative acute renal failure were significantly increased in the RVF group compared with the control group. The survival after LVAD implantation was 33.5%±9.0% and 85.4%±6.0% at 1 year in the RVF and control groups, respectively (P<0.0001).
conclusionsLVAD implantation by thoracotomy significantly reduced the risk of postoperative RVF. This surgical approach should, therefore, be favored.
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