Evidence map›Paper›PMID 32395252›Full record

ArticleOxford medical case reports2020

Successful intervention for overwhelming postsplenectomy infection caused by non-vaccine pneumococcal serotype 23A.

Yuichi Kojima, Kazuna Ikeda, Akihiro Matsumura, Shun Shimohama, Bin Chang, Takayuki Yoshida, Kunio Hamada, Akihide Ito, Toshiki Ito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxford medical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuichi KojimaDivision of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.
Kazuna IkedaDepartment of Neurology, School of Medicine, Sapporo Medical University, Sapporo 060-8543, Japan.
Akihiro MatsumuraDepartment of Neurology, School of Medicine, Sapporo Medical University, Sapporo 060-8543, Japan.
Shun ShimohamaDepartment of Neurology, School of Medicine, Sapporo Medical University, Sapporo 060-8543, Japan.
Bin ChangDepartment of Bacteriology 1, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Takayuki YoshidaDivision of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.
Kunio HamadaDivision of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.
Akihide ItoDivision of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.
Toshiki ItoDivision of Internal Medicine, Department of Internal Medicine, Chitose City Hospital, Hokkaido 066-8550, Japan.ORCID 0000-0002-2188-0516
Sapporo Medical University · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spleen plays an important role in the body's immune defense against invasive infections, particularly those caused by encapsulated bacteria. Encapsulated bacterial infection in asplenic patients is a medical emergency called overwhelming postsplenectomy infection (OPSI) and has a mortality rate of 50-70%. Here, we report the case of a 51-year-old Asian man who complained of emesis and diarrhea as primary symptoms. He rapidly progressed to coma and was eventually diagnosed with OPSI (pyogenic ventriculitis/spondylitis) caused by non-vaccine pneumococcal serotype 23A. Aggressive management, including empiric antibiotic therapy, a staircase approach for intracranial pressure-targeted therapy and laminectomy/laminoplasty, resulted in a good recovery. Our report highlights that non-vaccine pneumococcal serotypes can cause disease in vaccinated patients.

Identifiers

PMID32395252
PMCPMC7202049
OpenAlexW3023636457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.