Evidence map›Paper›PMID 32394884›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Substandard and Falsified Antibiotics and Medicines against Noncommunicable Diseases in Western Cameroon and Northeastern Democratic Republic of Congo.

Simon Schäfermann, Cathrin Hauk, Emmanuel Wemakor, Richard Neci, Georges Mutombo, Edward Ngah Ndze, Tambo Cletus, Fidelis Nyaah, Manyi Pattinora, Dorothee Wistuba and 4 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Quality of Essential Medicines from Different Sources in Enugu and Anambra, Nigeria.The American journal of tropical medicine and hygiene · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Assessment of the Quality of Injectable Antibiotics in Benin.The American journal of tropical medicine and hygiene · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Simon Schäfermann1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Cathrin Hauk1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Emmanuel Wemakor1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Richard Neci2Le Dépôt Central Médico-Pharmaceutique de la 8e CEPAC (DCMP), Bukavu, Democratic Republic of Congo.
Georges Mutombo2Le Dépôt Central Médico-Pharmaceutique de la 8e CEPAC (DCMP), Bukavu, Democratic Republic of Congo.
Edward Ngah Ndze3Cameroon Baptist Convention (CBC), Central Pharmacy, Mutengene, Cameroon.
Tambo Cletus3Cameroon Baptist Convention (CBC), Central Pharmacy, Mutengene, Cameroon.
Fidelis Nyaah4Presbyterian Church in Cameroon (PCC), Central Pharmacy, Limbe, Cameroon.
Manyi Pattinora4Presbyterian Church in Cameroon (PCC), Central Pharmacy, Limbe, Cameroon.
Dorothee Wistuba5Institute of Organic Chemistry, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Irina Helmle1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Christine Häfele-Abah6German Institute for Medical Mission (Difaem), Tuebingen, Germany.
Harald Gross1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Lutz Heide1Pharmaceutical Institute, Eberhard Karls University Tuebingen, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Falsified and substandard medicines may undermine the progress toward the Sustainable Development Goals. The present study investigated the quality of 13 essential medicines in Cameroon and the Democratic Republic of Congo (DR Congo). Five hundred six medicine samples were collected from the government and faith-based health facilities, private pharmacies, and informal vendors (total 60 facilities). Collected samples were analyzed according to the U.S. Pharmacopeia (USP) for identity, content, and dissolution of their active pharmaceutical ingredients (APIs) and for uniformity of dosage units. Three samples (0.6%) were identified as falsified. Overall, 8.5% of the samples failed USP specifications for the content of the API and 11.7% failed dissolution testing. Medicines from informal vendors showed a higher out-of-specification rate (28.2%) than other types of drug outlets (12.3%;

Indexed as

Counterfeit DrugsSubstandard DrugsAdrenergic beta-1 Receptor AntagonistsAdrenergic beta-2 Receptor AgonistsAnti-Bacterial AgentsAntihypertensive AgentsCameroonChromatography, High Pressure LiquidDemocratic Republic of the CongoDiureticsDrugs, EssentialHumansHypoglycemic AgentsAdrenergic beta-1 Receptor AntagonistsAdrenergic beta-2 Receptor AgonistsAnti-Bacterial AgentsAntihypertensive AgentsCounterfeit DrugsDiureticsDrugs, EssentialHypoglycemic AgentsSubstandard Drugs

Identifiers

PMID32394884
PMCPMC7410427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.