Evidence map›Paper›PMID 32394803›Full record

ArticleSocial neuroscience2021

The social regulation of emotion: Inconsistencies suggest no mediation through ventromedial prefrontal cortex.

Lane A Beckes, Sara E Medina-DeVilliers, James A Coan

Abstract read
In one paragraph

Article in Social neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lane A BeckesDepartment of Psychology, Bradley University , Peoria, USA.ORCID 0000-0003-0375-2526
Sara E Medina-DeVilliersDepartment of Psychology, University of Virginia , Charlottesville, USA.
James A CoanDepartment of Psychology, University of Virginia , Charlottesville, USA.

Funding

Neural Mechanisms of Social Emotion RegulationR01MH080725 · NIMH · UNIVERSITY OF VIRGINIA · PI COAN, JAMES A · 2009 to 2012
$1.3M
NIMH NIH HHS R01 MH080725
6 · The paper itself

Abstract

Physical touch in the form of holding a loved one's hand attenuates the neural response to threat. Speculation regarding the neural mediation of this effect points to the ventromedial prefrontal cortex (vmPFC), which is known to have inhibitory connections with threat responsive brain regions such as the amygdala. Despite the attractiveness of this hypothesis, a link between the vmPFC and diminished threat during handholding has been difficult to demonstrate empirically. Here we report that in a sample of 110 participants no evidence for vmPFC mediation of the handholding effect was obtained. Indeed, results indicated that connectivity patterns between threat responsive salience network structures and the vmPFC were in the opposite direction one would predict if the vmPFC mediated reductions in neural threat-responding caused by partner handholding. Our findings suggest that the vmPFC does not mediate the regulating effect of physical contact on neural threat responses.

Indexed as

Brain MappingMagnetic Resonance ImagingAmygdalaEmotionsHumansPrefrontal Cortexclose relationshipsEmotion regulationhandholdingsocial baselinethreatvmPFC

Identifiers

PMID32394803
PMCPMC7738398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.