Evidence map›Paper›PMID 32394723›Full record

Trial reportAIDS research and human retroviruses2020

Effects of Depot Medroxyprogesterone Acetate, Copper Intrauterine Devices, and Levonorgestrel Implants on Early HIV Disease Progression.

Charles S Morrison, G Justus Hofmeyr, Katherine K Thomas, Helen Rees, Neena Philip, Thesla Palanee-Phillips, Kavita Nanda, Gonasagrie Nair, Maricianah Onono, Timothy D Mastro and 10 more

Open access · hybridAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS research and human retroviruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 4 countries.

Charles S MorrisonFHI 360, Durham, North Carolina, USA.
G Justus HofmeyrEffective Care Research Unit, Department of Obstetrics and Gynaecology, University of Witwatersrand/Fort Hare/Walter Sisulu, East London, South Africa.
Katherine K ThomasDepartment of Global Health, University of Washington, Seattle, USA.
Helen ReesWits Reproductive Health and HIV Institute (Wits RHI), University of Witswatersrand, Johannesburg, South Africa.
Neena PhilipMailman School of Public Health, ICAP at Columbia University, New York, USA.
Thesla Palanee-PhillipsWits Reproductive Health and HIV Institute (Wits RHI), University of Witswatersrand, Johannesburg, South Africa.
Kavita NandaFHI 360, Durham, North Carolina, USA.
Gonasagrie NairEmavundleni Research Center, Capetown, South Africa.
Maricianah OnonoKEMRI-RCTP Study Center, Kisumu, Kenya.
Timothy D MastroFHI 360, Durham, North Carolina, USA.
Maggie LindDepartment of Global Health, University of Washington, Seattle, USA.
Renee HeffronDepartment of Global Health, University of Washington, Seattle, USA.
Vinodh EdwardThe Aurum Institute, Johannesburg, South Africa.
Jen DeeseFHI 360, Durham, North Carolina, USA.
Mags BeksinskaMatCH Research Unit (MRU), Faculty of Health Sciences, Department of Obstetrics and Gynecology, University of the Witwatersrand, Durban, South Africa.
Ivana BeeshamMatCH Research Unit (MRU), Faculty of Health Sciences, Department of Obstetrics and Gynecology, University of the Witwatersrand, Durban, South Africa.
Jeffrey S A StringerDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Jared M BaetenDepartment of Global Health, University of Washington, Seattle, USA.
Khatija AhmedSetshaba Research Center, Soshanguve, South Africa.
ECHO Trial Team
University of the Witwatersrand · ZAFamily Health International 360 · USSeattle University · USUniversity of Washington · USColumbia University · USDepartment of Agriculture, Land Reform and Rural Development · ZAGreat Lakes University of Kisumu · KESetshaba Research Centre · ZAUniversity of Fort Hare · ZAUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited data exist on the effects of contraceptives on HIV disease progression. We studied the association between intramuscular injectable depot medroxyprogesterone acetate (DMPA-IM), the copper intrauterine device (IUD), and the levonorgestrel (LNG) implant on markers of HIV disease progression at the time of HIV detection and 3 months postdetection and time from detection to CD4 count <350 cells/mm

Indexed as

AdolescentAdultCD4 Lymphocyte CountDisease ProgressionFemaleHIV InfectionsHormonal ContraceptionHumansIntrauterine Devices, CopperLevonorgestrelMedroxyprogesterone AcetateProportional Hazards ModelsViral LoadYoung AdultLevonorgestrelMedroxyprogesterone Acetatedisease progressionDMPAHIVhormonal contraceptionimplantsintrauterine deviceviral suppression

Identifiers

PMID32394723
PMCPMC7414801
OpenAlexW3024849984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.