Evidence map›Paper›PMID 32394670›Full record

ArticleBiomolecules & therapeutics2020

Anti-Proliferative Activity of Nodosin, a Diterpenoid from

Eun Seo Bae, Young-Mi Kim, Dong-Hwa Kim, Woong Sub Byun, Hyen Joo Park, Young-Won Chin, Sang Kook Lee

Open access · greenAbstract read
In one paragraph

Article in Biomolecules & therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Bioactive polyphenols fromRSC advances · 2026
    Article
  2. Review
  3. Diterpenoids from the Aerial Parts ofMolecules (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eun Seo BaeCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Young-Mi KimCollege of Pharmacy, Research Institute of Pharmaceutical Science, Seoul National University, Seoul 08826, Republic of Korea.
Dong-Hwa KimCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Woong Sub ByunCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Hyen Joo ParkCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Young-Won ChinCollege of Pharmacy, Research Institute of Pharmaceutical Science, Seoul National University, Seoul 08826, Republic of Korea.
Sang Kook LeeCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea.
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most malignant type of cancers and its incidence is steadily increasing, due to life style factors that include western diet. Abnormal activation of canonical Wnt/β-catenin signaling pathway plays an important role in colorectal carcinogenesis. Therefore, targeting Wnt/β-catenin signaling has been considered a crucial strategy in the discovery of small molecules for CRC. In the present study, we found that Nodosin, an

Indexed as

Anti-proliferative activityApoptosisColon cancer cellsIsodon serraNodosinWnt/β-catenin signaling pathway

Identifiers

PMID32394670
PMCPMC7457175
OpenAlexW3026001394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.