Evidence map›Paper›PMID 32394576›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2020

Transdiagnostic clinical staging in youth mental health: a first international consensus statement.

Jai L Shah, Jan Scott, Patrick D McGorry, Shane P M Cross, Matcheri S Keshavan, Barnaby Nelson, Stephen J Wood, Steven Marwaha, Alison R Yung, Elizabeth M Scott and 5 more

Abstract read
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  18. Taking care of psychotic disorders globally, beyond clinical management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  19. Child and adolescent psychiatry: challenges, solutions, opportunities, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  20. Real-world comprehensive care of people living with schizophrenia: recommendations across different settings and clinical stages.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jai L ShahPrevention and Early Intervention Program for Psychosis (PEPP-Montreal), Douglas Mental Health University Institute, Montreal, QC, Canada.
Jan ScottInstitute of Neuroscience, University of Newcastle, Newcastle upon Tyne, UK.
Patrick D McGorryOrygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia.
Shane P M CrossBrain and Mind Centre, University of Sydney, Sydney, NSW, Australia.
Matcheri S KeshavanMassachusetts Mental Health Center and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Barnaby NelsonOrygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia.
Stephen J WoodOrygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia.
Steven MarwahaInstitute for Mental Health, University of Birmingham, Birmingham, UK.
Alison R YungOrygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia.
Elizabeth M ScottBrain and Mind Centre, University of Sydney, Sydney, NSW, Australia.
Dost ÖngürPsychotic Disorders Division, McLean Hospital, Harvard Medical School, Boston, MA, USA.
Philippe ConusTreatment and Early Intervention in Psychosis Program (TIPP), Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.
Chantal HenryPerception and Memory Unit, Institut Pasteur, UMR3571, Centre National de la Recherche Scientifique (CNRS), Paris, France.
Ian B HickieBrain and Mind Centre, University of Sydney, Sydney, NSW, Australia.
International Working Group on Transdiagnostic Clinical Staging in Youth Mental Health

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recognizing that current frameworks for classification and treatment in psychiatry are inadequate, particularly for use in young people and early intervention services, transdiagnostic clinical staging models have gained prominence. These models aim to identify where individuals lie along a continuum of illness, to improve treatment selection and to better understand patterns of illness continuity, discontinuity and aetiopathogenesis. All of these factors are particularly relevant to help-seeking and mental health needs experienced during the peak age range of onset, namely the adolescent and young adult developmental periods (i.e., ages 12-25 years). To date, progressive stages in transdiagnostic models have typically been defined by traditional symptom sets that distinguish "sub-threshold" from "threshold-level" disorders, even though both require clinical assessment and potential interventions. Here, we argue that staging models must go beyond illness progression to capture additional dimensions of illness extension as evidenced by emergence of mental or physical comorbidity/complexity or a marked change in a linked biological construct. To develop further consensus in this nascent field, we articulate principles and assumptions underpinning transdiagnostic clinical staging in youth mental health, how these models can be operationalized, and the implications of these arguments for research and development of new service systems. We then propose an agenda for the coming decade, including knowledge gaps, the need for multi-stakeholder input, and a collaborative international process for advancing both science and implementation.

Indexed as

Clinical stagingextensionhealth servicesheterotypyhomotypyprogressionservice trans­formationtransdiagnosticyouth mental health

Identifiers

PMID32394576
PMCPMC7215079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.