Evidence map›Paper›PMID 32394473›Full record

ArticleJournal of the peripheral nervous system : JPNS2020

Validation of the Italian version of the Charcot-Marie-Tooth disease Pediatric Scale.

Riccardo Zuccarino, Valeria Prada, Isabella Moroni, Emanuela Pagliano, Maria Foscan, Giulia Robbiano, Chiara Pisciotta, Kayla Cornett, Rosemary Shy, Angelo Schenone and 3 more

Open access · greenAbstract readValidation Study
In one paragraph

Article in Journal of the peripheral nervous system : JPNS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Multidimensional evaluation of clinical and functional impairment in a large population of patients with Charcot-Marie-Tooth.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Riccardo ZuccarinoDepartment of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.ORCID 0000-0002-8481-7899
Valeria PradaDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal/Child Sciences, University of Genova and IRCCS San Martino, Genoa, Italy.ORCID 0000-0001-5756-0576
Isabella MoroniFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Emanuela PaglianoFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Maria FoscanFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Giulia RobbianoDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal/Child Sciences, University of Genova and IRCCS San Martino, Genoa, Italy.
Chiara PisciottaFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Kayla CornettUniversity of Sydney School of Health Sciences & Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Rosemary ShyDepartment of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Angelo SchenoneDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal/Child Sciences, University of Genova and IRCCS San Martino, Genoa, Italy.
Davide PareysonFondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Michael ShyDepartment of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Joshua BurnsUniversity of Sydney School of Health Sciences & Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Fondazione IRCCS Istituto Neurologico Carlo Besta · ITOspedale Policlinico San Martino · ITUniversity of Iowa · USThe University of Sydney · AU

Funding

trainingU54NS065712 · NINDS · WAYNE STATE UNIVERSITY · PI SHY, MICHAEL E. · 2009 to 2023
$19.6M
Genomic Studies in Charcot-Marie-Tooth DiseaseR01NS105755 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SHY, MICHAEL E., ZUCHNER, STEPHAN · 2019 to 2023
$3.2M
Clinical Trial Readiness for Rare Diseases, Disorders and SyndromesR21TR003034 · NCATS · UNIVERSITY OF IOWA · PI SHY, MICHAEL E. · 2019 to 2020
$418k
Foundation for the National Institutes of Health U54NS065712NCATS NIH HHS R21 TR003034NINDS NIH HHS R01 NS105755NINDS NIH HHS R21TR003034NINDS NIH HHS U54 NS065712
6 · The paper itself

Abstract

The Charcot-Marie-Tooth disease Pediatric Scale (CMTPedS) is a Rasch-built clinical outcome measure of disease severity. It is valid, reliable, and responsive to change for children and adolescents aged 3 to 20 years. The aim of this study was to translate and validate an Italian version of the CMTPedS using a validated framework of transcultural adaptation. The CMTPedS (Italian) was translated and culturally adapted from source into Italian by two experts in CMT with good English language proficiency. The two translations were reviewed by a panel of experts in CMT. The agreed provisional version was back translated into English by a professional translator. The definitive Italian version was developed during a consensus teleconference by the same panel. CMT patients were assessed with the final version of the outcome measure and a subset had a second assessment after 2 weeks to evaluate test-retest reliability. Seventeen patients with CMT aged 5 to 20 years (eight female) were evaluated with the CMTPedS (Italian), and test-retest was performed in three patients. The CMTPedS (Italian) showed a high test-retest reliability. No patient had difficulty in completing the scale. The instructions for the different items were clearly understood by clinicians and therefore the administration of the outcome measure was straight forward and easily understood by the children assessed. The CMTPedS (Italian) will be used for clinical follow-up and in clinical research studies in the Italian population. The data is fully comparable to that obtained from the English language version.

Indexed as

Severity of Illness IndexAdolescentAdultCharcot-Marie-Tooth DiseaseChildChild, PreschoolFemaleHumansItalyMaleOutcome Assessment, Health CarePsychometricsReproducibility of ResultsTranslatingYoung AdultCharcot-Marie-tooth diseaseclinical outcome assessmentCMTPedSoutcome measurestranslation

Identifiers

PMID32394473
PMCPMC11725311
OpenAlexW3024209061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.