Evidence map›Paper›PMID 32394354›Full record

ArticleBiological trace element research2021

Effects of Nano-Zinc on Immune Function in Qianbei-Pockmarked Goats.

Chunjie Song, Shangquan Gan, Jian He, Xiaoyun Shen

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Chunjie SongSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China.
Shangquan GanState Key Laboratory of Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Sciences, Shihezi, Xinjiang, 832000, China.
Jian HeSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China.
Xiaoyun ShenSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China. xyshen@swust.edu.cn.ORCID http://orcid.org/0000-0003-2797-7981
Southwest University of Science and Technology · CNXinjiang Academy of Agricultural and Reclamation Science · CN

Funding

the National Natural Science Foundation of China 41671041the Project of National Key Research and Development Program of China in 13th Five-year Plan 2016YFC0502601
6 · The paper itself

Abstract

Qianbei-pockmarked goats are vital to the production system of western China. This study aimed to determine the influence of nano-zinc on immune function in zinc-deprived goats. We analyzed the mineral concentrations in soil, forage, and animal tissue. Blood parameters and immune indexes were also determined. Results showed that the zinc concentrations in soil and forage from affected area were significantly lower than those in control area (P < 0.01). Zinc contents in tissues (blood and hair) from affected Qianbei-pockmarked goats were also significantly lower than those in healthy animals (P < 0.01). Levels of hemoglobin, erythrocyte count, and packed cell volume from affected animals were markedly lower than those in healthy animals (P < 0.01). Levels of lactate dehydrogenase, alkaline phosphatase, superoxide dismutase, glutathione peroxide, catalase, and total antioxidant capacity in serum in affected animals were significantly lower, and aspartate aminotransferase, alanine transaminase, malondialdehyde in serum were significantly higher than those in healthy goats (P < 0.01). The contents of immunoglobulin A, immunoglobulin M, immunoglobulin G, interleukin-2, interleukin 6, and interleukin-1β from affected animals were significantly lower than those in healthy animals (P < 0.01). The affected Qianbei-pockmarked goats were treated orally with nano-zinc, the concentration of zinc in blood significantly increased, and serum immune indexes greatly returned to that within the healthy range. It was concluded that nano-zinc could not only markedly increase the zinc content in blood of zinc-deprived goats but also much improve the immune function.

Indexed as

GoatsZincAnimalsAntioxidantsChinaImmunityAntioxidantsZincBlood parametersImmunityNano-zincThe Qianbei-pockmarked goatsZinc deprivation

Identifiers

PMID32394354
OpenAlexW3025115450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.