Evidence map›Paper›PMID 32394234›Full record

ArticleClinical & experimental metastasis2020

Development of

Thiago Barboza, Tainá Gomes, Priscylla da Costa Medeiros, Isalira Peroba Ramos, Ivo Francischetti, Robson Q Monteiro, Bianca Gutfilen, Sergio Augusto Lopes de Souza

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical & experimental metastasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Thiago BarbozaDepartamento de Radiologia, Faculdade de Medicina, Laboratório de Marcação de Células E Moléculas, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Tainá GomesInstituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Priscylla da Costa MedeirosDepartamento de Radiologia, Faculdade de Medicina, Laboratório de Marcação de Células E Moléculas, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Isalira Peroba RamosCentro Nacional de Bioimagem E Biologia Estrutural, Bloco M, Unidade 2, Centro de Ciências da Saúde, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Ivo FrancischettiLaboratory of Malaria and Vector Research, NIAID, National Institutes of Health, Bethesda, USA.
Robson Q MonteiroInstituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Bianca GutfilenDepartamento de Radiologia, Faculdade de Medicina, Laboratório de Marcação de Células E Moléculas, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil.
Sergio Augusto Lopes de SouzaDepartamento de Radiologia, Faculdade de Medicina, Laboratório de Marcação de Células E Moléculas, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, Brasil. sergioalsouza@gmail.com.ORCID http://orcid.org/0000-0002-7901-4805
Universidade Federal do Rio de Janeiro · BRNational Institute of Science and Technology for Structural Biology and Bioimaging · BRNational Institutes of Health · USUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue factor (TF), a blood coagulation protein, plays an important role in tumor growth, invasion, and metastasis. Ixolaris, a tick-derived non-immunogenic molecule that binds to TF, has demonstrated in vivo inhibitory effect on murine models of melanoma, including primary growth and metastasis. This work aimed to: I) develop an efficient and stable labeling technique of ixolaris with Iodine-131(

Indexed as

AnimalsAnticoagulantsBlood CoagulationCell Line, TumorDisease Models, AnimalIodine RadioisotopesMelanoma, ExperimentalMiceMice, Inbred C57BLPrecision MedicineSalivary Proteins and PeptidesThromboplastinAnticoagulantsIodine-131Iodine RadioisotopesIxolaris protein, Ixodes scapularisSalivary Proteins and PeptidesThromboplastin131-IIxolarisMetastatic melanomaScintigraphyTheranostic

Identifiers

PMID32394234
OpenAlexW3024199380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.