Evidence map›Paper›PMID 32394219›Full record

Trial reportInternational journal of behavioral medicine2020

The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers: a Randomized Controlled Trial.

Elina Järvelä-Reijonen, Sampsa Puttonen, Leila Karhunen, Essi Sairanen, Jaana Laitinen, Mikko Kolehmainen, Jussi Pihlajamäki, Urho M Kujala, Riitta Korpela, Miikka Ermes and 2 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of behavioral medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01738256 (Applicability and Efficiency of Different Approaches in Lifestyle Interventions - Lifestyle Management and Changes in Everyday Life), which is not on this map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
1.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01738256 nacompletednot on this map

Applicability and Efficiency of Different Approaches in Lifestyle Interventions - Lifestyle Management and Changes in Everyday Life

TypeinterventionalSponsorUniversity of JyvaskylaRan2012 to 2013Enrolled339ConditionsMetabolic Syndrome Risk Factors, Overweight, Psychological StressArmsWellbeing intervention (ACT), Wellbeing intervention (Internet), No intervention
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Elina Järvelä-ReijonenInstitute of Public Health and Clinical Nutrition, Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland. elina.jarvela-reijonen@uef.fi.ORCID https://orcid.org/0000-0002-9346-3340
Sampsa PuttonenFinnish Institute of Occupational Health, P.O. Box 40, FI-00251, Helsinki, Finland.
Leila KarhunenInstitute of Public Health and Clinical Nutrition, Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
Essi SairanenDepartment of Psychology, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland.
Jaana LaitinenFinnish Institute of Occupational Health, P.O. Box 40, FI-00251, Helsinki, Finland.
Mikko KolehmainenDepartment of Environmental and Biological Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
Jussi PihlajamäkiInstitute of Public Health and Clinical Nutrition, Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
Urho M KujalaFaculty of Sport and Health Sciences, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland.
Riitta KorpelaMedical Faculty, Pharmacology, Medical Nutrition Physiology and Human Microbe Research Program, University of Helsinki, P.O. Box 63, FI-00014, Helsinki, Finland.
Miikka ErmesInstitute of Public Health and Clinical Nutrition, Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
Raimo LappalainenDepartment of Psychology, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland.
Marjukka KolehmainenInstitute of Public Health and Clinical Nutrition, Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211, Kuopio, Finland.
University of Eastern Finland · FIFinnish Institute of Occupational Health · FIUniversity of Jyväskylä · FIKarlstad University · SEUniversity of Helsinki · FI

Funding

Doctoral Programme in Nutrition of the Faculty of Health Sciences, University of Eastern Finland N/APohjois-Savon Rahasto N/ATekes 1104/10
6 · The paper itself

Abstract

backgroundPsychological processes can be manifested in physiological health. We investigated whether acceptance and commitment therapy (ACT), targeted on psychological flexibility (PF), influences inflammation and stress biomarkers among working-age adults with psychological distress and overweight/obesity.

methodParticipants were randomized into three parallel groups: (1) ACT-based face-to-face (n = 65; six group sessions led by a psychologist), (2) ACT-based mobile (n = 73; one group session and mobile app), and (3) control (n = 66; only the measurements). Systemic inflammation and stress markers were analyzed at baseline, at 10 weeks after the baseline (post-intervention), and at 36 weeks after the baseline (follow-up). General PF and weight-related PF were measured with questionnaires (Acceptance and Action Questionnaire, Acceptance and Action Questionnaire for Weight-Related Difficulties).

resultsA group × time interaction (p = .012) was detected in the high-sensitivity C-reactive protein (hsCRP) level but not in other inflammation and stress biomarkers. hsCRP decreased significantly in the face-to-face group from week 0 to week 36, and at week 36, hsCRP was lower among the participants in the face-to-face group than in the mobile group (p = .035, post hoc test). Age and sex were stronger predictors of biomarker levels at follow-up than the post-intervention PF.

conclusionThe results suggest that ACT delivered in group sessions may exert beneficial effects on low-grade systemic inflammation. More research is needed on how to best apply psychological interventions for the health of both mind and body among people with overweight/obesity and psychological distress.

trial registrationClinicalTrials.gov Identifier: NCT01738256, Registered 17 August, 2012.

Indexed as

Acceptance and Commitment TherapyAdultBiomarkersHumansInflammationObesityOverweightBiomarkersACTLow-grade inflammationMindfulnessObesityPsychological flexibilityStress

Identifiers

PMID32394219
PMCPMC7497453
OpenAlexW3025534555

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.