SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2021
Gastric per-Oral Endoscopic Myotomy for Refractory Gastroparesis: A Meta-Analysis.
Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Gastric per-oral endoscopic myotomy versus pyloric injection of botulinum toxin for the treatment of gastroparesis: our institutional experience and a systematic review of the literature.Surgical endoscopy · 2023Pooled it
- Trial
- POEtry in Motion: G-POEM Effectively Relieves Gastroparesis in a Rare Case of Combined Wilkie and Nutcracker Syndromes.Digestive diseases and sciences · 2026Article
- Efficacy of gastric per oral endoscopic myotomy for gastroparesis symptoms.Surgical endoscopy · 2026Article
- Review
- Pyloric Dysfunction: A Review of the Mechanisms, Diagnosis, and Treatment.Gut and liver · 2025Review
- Factor analysis of postsurgical gastroparesis syndrome after right hemicolectomy for colon cancer.Oncology letters · 2025Article
- Outcomes after per oral pyloromyotomy based on gastroparesis etiology.Surgical endoscopy · 2025Article
- A long-term follow-up study of gastric peroral endoscopic myotomy (G-POEM) in a large cohort of patients with postsurgical gastroparesis.Surgical endoscopy · 2024Article
- Impedance planimetry during per-oral endoscopic myotomy is associated with decreased inadvertent capnoperitoneum.Surgical endoscopy · 2024Article
- Predictors of favorable outcome after pyloroplasty for gastroparesis: should response to pyloric dilation or Botox injection be used as a marker of surgical outcome?Surgical endoscopy · 2023Article
- Reconsideration of the Gastroparetic Syndrome.Current gastroenterology reports · 2023Review
- Gastric peroral endoscopic pyloromyotomy (G-POEM) in patients with refractory gastroparesis: a review.Therapeutic advances in gastroenterology · 2023Review
- Endoscopic treatment modalities for the management of gastroparesis: a critical review.Annals of gastroenterologyReview
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe emerging gastric per-oral endoscopic myotomy (G-POEM) is becoming an alternative treatment method for gastroparesis. This study aimed to evaluate the feasibility and safety of G-POEM for gastroparesis.
methodsRelevant publications were identified through searching PubMed, EMBASE, Cochrane Library, and Web of Science before April 1, 2019. Studies presenting the clinical data of G-POEM for the treatment of gastroparesis were included. Data about effectiveness and safety were extracted, pooled, and analyzed. Forest plots were graphed based on random effects models.
resultsA total of 272 patients representing 8 studies were eligible for analysis. The pooled rates of GCSI at preprocedure, 1-3 months, 6 months, and 12 months, were 3.25 (95% CI, 2.75-3.75), 1.80 (95% CI, 1.10-2.49), 1.56 (95% CI, 0.45-2.68), and 1.10 (95% CI, 0.75-1.45), respectively. The pooled results of 4-h GES pre- and post-G-POEM were 41.89% (95% CI, 32.75-51.03%) and 16.48% (95% CI, 9.83-23.14%), respectively. Furthermore, the pooled clinical response rate was 84% (95% CI, 77-89%). The GES improvement rate and GES normal rate were also analyzed, and the results were 84% (95% CI, 77-90%) and 53% (95% CI, 39-66%), respectively. Finally, the pooled adverse events rate was 12% (95% CI, 6-19%).
conclusionsG-POEM was shown to be feasible and safe for the treatment of gastroparesis with various etiologies, which could be a potential first-line therapy for certain patients. Future studies are needed to investigate the appropriate patients for G-POEM to explore the "most beneficial" subgroup of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.