ArticleJournal of cancer survivorship : research and practice2020
Quality of life and the negative impact of comorbidities in long-term colorectal cancer survivors: a population-based comparison.
Article in Journal of cancer survivorship : research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Interventions to Reduce Sedentary Behavior in Cancer Patients and Survivors: a Systematic Review.Current oncology reports · 2022Pooled it
- Clustering on longitudinal quality-of-life measurements using growth mixture models for clinical prognosis: Implementation on CCTG/AGITG CO.20 trial.Cancer medicine · 2023Trial
- Health-related quality of life and lifestyle in long-term survivors of colorectal cancer and a matched non-cancer reference group.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- A qualitative exploration of perioperative subjective experiences of colorectal cancer patients undergoing fast-track surgery.Scientific reports · 2024Article
- Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors.Healthcare (Basel, Switzerland) · 2024Article
- General population normative values for the EORTC QLQ-C30 by age, sex, and health condition for the French general population.Journal of patient-reported outcomes · 2024Article
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- Cancer survivors' health behaviors and outcomes: a population-based study of sexual and gender minorities.Journal of the National Cancer Institute · 2023Article
- Multimorbidity in people living with and beyond cancer: a scoping review.American journal of cancer research · 2023Article
- Biofeedback therapy combined with Baduanjin on quality of life and gastrointestinal hormone level in patients with colorectal cancer.World journal of gastrointestinal oncology · 2022Article
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- Article
- Symptom burden, psychological distress, and health-related quality of life in cancer survivors with pelvic late radiation tissue injuries.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeColorectal cancer (CRC) is the third most common cancer in the USA. The objective of this study was to compare quality of life (QoL) across long-term colorectal cancer survivors and unaffected matched controls while adjusting for comorbidities.
methodsThe National Cancer Institute (NCI)-funded Colon Cancer Family Registry (CCFR) was used to randomly select and recruit CRC survivors (≥ 5 years from diagnosis) and matched controls for a cross-sectional survey. Nine geographically diverse sites in the USA from the CCFR participated in the study. Telephone interviews were conducted using computer-assisted methods to assess QoL.
resultsA total of 403 cases and 401 controls were included in the final sample. Unadjusted comparison revealed no significant difference between CRC survivors and controls with respect to measures of fatigue, social, emotional, functional, and physical well-being. Multivariate logistic regression revealed that case status had a significant negative influence on colorectal cancer-specific QoL measures. Higher comorbidity indices had a significant negative influence on overall QoL regardless of case status.
conclusionsQuality of life among long-term CRC survivors is similar to control subjects, with the exception of worse CRC-specific QoL measures. Higher comorbidity indices were independently associated with poor QoL for both cases and controls. IMPLICATIONS FOR CANCER SURVIVORS: Survivors and healthcare providers should be aware that long-term QoL is comparable to the general population; however, there is potential that digestive tract-specific issues may persist.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.