Evidence map›Paper›PMID 32393884›Full record

ArticleNature cell biology2020

Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin.

Michael Borg, Yannick Jacob, Daichi Susaki, Chantal LeBlanc, Daniel Buendía, Elin Axelsson, Tomokazu Kawashima, Philipp Voigt, Leonor Boavida, Jörg Becker and 3 more

Open access · greenAbstract read
In one paragraph

Article in Nature cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 1 pooled it
33.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 1 synthesis or guideline pooled it, 225 citations in OpenAlex.

  1. Pooled it
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  20. Epigenetics in the modern era of crop improvements.Science China. Life sciences · 2025
    Review

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Michael BorgGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Yannick JacobHoward Hughes Medical Institute-Gordon and Betty Moore Foundation, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, New York, NY, USA.
Daichi SusakiInstitute of Transformative Bio-Molecules (WPI-ITbM), Graduate School of Science, Nagoya University, Nagoya, Japan.ORCID http://orcid.org/0000-0002-9465-9222
Chantal LeBlancDepartment of Molecular, Cellular and Developmental Biology, Faculty of Arts and Sciences, Yale University, New Haven, CT, USA.
Daniel BuendíaGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.ORCID http://orcid.org/0000-0001-7917-3155
Elin AxelssonGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.
Tomokazu KawashimaGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.ORCID http://orcid.org/0000-0003-3803-3070
Philipp VoigtWellcome Trust Centre for Cell Biology, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-4366-0490
Leonor BoavidaInstituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID http://orcid.org/0000-0001-6555-0685
Jörg BeckerInstituto Gulbenkian de Ciência, Oeiras, Portugal.
Tetsuya HigashiyamaInstitute of Transformative Bio-Molecules (WPI-ITbM), Graduate School of Science, Nagoya University, Nagoya, Japan.
Robert MartienssenHoward Hughes Medical Institute-Gordon and Betty Moore Foundation, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, New York, NY, USA.ORCID http://orcid.org/0000-0003-1285-9608
Frédéric BergerGregor Mendel Institute, Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria. frederic.berger@gmi.oeaw.ac.at.ORCID http://orcid.org/0000-0002-3609-8260
Gregor Mendel Institute of Molecular Plant Biology · ATHoward Hughes Medical Institute · USNagoya University · JPInstituto Gulbenkian de Ciência · PTPurdue University West Lafayette · USWellcome Centre for Cell Biology · GBYale University · US

Funding

Transposons, RNA Interference and HeterochromatinR01GM067014 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2003 to 2016
$4.1M
Austrian Science Fund FWF I 4258Austrian Science Fund FWF M 1818Austrian Science Fund FWF P 26887Austrian Science Fund FWF P 32054European Research Council 639253Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM067014Wellcome Trust 104175Wellcome Trust 104175/Z/14/ZWellcome Trust 203149
6 · The paper itself

Abstract

Epigenetic marks are reprogrammed in the gametes to reset genomic potential in the next generation. In mammals, paternal chromatin is extensively reprogrammed through the global erasure of DNA methylation and the exchange of histones with protamines

Indexed as

Cellular ReprogrammingDNA MethylationEpigenesis, GeneticAmino Acid SequenceArabidopsisArabidopsis ProteinsChromatinHistonesLysineProtein Processing, Post-TranslationalSequence HomologyArabidopsis ProteinsChromatinHistonesLysine

Identifiers

PMID32393884
PMCPMC7116658
OpenAlexW3021509493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.