ArticleNature plants2020
A molecular framework underlying the compound leaf pattern of Medicago truncatula.
Article in Nature plants, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 58 citations in OpenAlex.
- New components in genetic regulation of age-dependent compound leaf architecture in pea.The New phytologist · 2026Article
- Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- SlBL4 is involved in leaf polarity development in tomato.Frontiers in plant science · 2026Article
- Identification and characterization of theFrontiers in plant science · 2026Article
- LEAFY demonstrates functions in reproductive development of the gametophyte but not the sporophyte of the fern Ceratopteris richardii.Development (Cambridge, England) · 2026Article
- Mining of Candidate Genes Associated with Leaf Shape Traits in Grapes.International journal of molecular sciences · 2024Article
- Leaf form diversity and evolution: a never-ending story in plant biology.Journal of plant research · 2024Review
- Genomic analysis of a spontaneous unifoliate mutant reveals gene candidates associated with compound leaf development in Vigna unguiculata [L] Walp.Scientific reports · 2024Article
- GRAS transcription factor PINNATE-LIKE PENTAFOLIATA2 controls compound leaf morphogenesis in Medicago truncatula.The Plant cell · 2024Article
- Rewiring of a KNOXI regulatory network mediated by UFO underlies the compound leaf development in Medicago truncatula.Nature communications · 2024Article
- Article
- Control of compound leaf patterning by MULTI-PINNATE LEAF1 (MPL1) in chickpea.Nature communications · 2023Article
- The developmental dynamics in cool season legumes with focus on chickpea.Plant molecular biology · 2023Review
- Review
- DNA barcoding and comparative RNA-Seq analysis provide new insights into leaf formation using a novel resource of high-yieldingFrontiers in plant science · 2023Article
- Article
- WOX family transcriptional regulators modulate cytokinin homeostasis during leaf blade development in Medicago truncatula and Nicotiana sylvestris.The Plant cell · 2022Article
- The upregulated LsKN1 gene transforms pinnately to palmately lobed leaves through auxin, gibberellin, and leaf dorsiventrality pathways in lettuce.Plant biotechnology journal · 2022Article
- Leaf Development inGenes · 2022Review
- Molecular mechanisms underlying leaf development, morphological diversification, and beyond.The Plant cell · 2022Review
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compound leaves show more complex patterns than simple leaves, and this is mainly because of a specific morphogenetic process (leaflet initiation and arrangement) that occurs during their development. How the relevant morphogenetic activity is established and modulated to form a proper pattern of leaflets is a central question. Here we show that the trifoliate leaf pattern of the model leguminous plant Medicago truncatula is controlled by the BEL1-like homeodomain protein PINNATE-LIKE PENTAFOLIATA1 (PINNA1). We identify PINNA1 as a determinacy factor during leaf morphogenesis that directly represses transcription of the LEAFY (LFY) orthologue SINGLE LEAFLET1 (SGL1), which encodes an indeterminacy factor key to the morphogenetic activity maintenance. PINNA1 functions alone in the terminal leaflet region and synergizes with another determinacy factor, the C2H2 zinc finger protein PALMATE-LIKE PENTAFOLIATA1 (PALM1), in the lateral leaflet regions to define the spatiotemporal expression of SGL1, leading to an elaborate control of morphogenetic activity. This study reveals a framework for trifoliate leaf-pattern formation and sheds light on mechanisms generating diverse leaf forms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.