Evidence map›Paper›PMID 32393829›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Clinical validity of systemic arterial steal among extremely preterm infants with persistent patent ductus arteriosus.

Lieke Keusters, Jyotsna Purna, Poorva Deshpande, Luc Mertens, Prakeshkumar Shah, Patrick J McNamara, Dany E Weisz, Amish Jain

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Cerebral and intestinal Doppler patterns according to patent ductus arteriosus shunt characteristics in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. The often forgotten systemic effects of ductus arteriosus: impact on decision-making and future trials.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Lieke KeustersDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Jyotsna PurnaDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Poorva DeshpandeDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Luc MertensDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.
Prakeshkumar ShahDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Patrick J McNamaraDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.
Dany E WeiszDepartment of Paediatrics, University of Toronto, Toronto, ON, Canada.
Amish JainDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada. amish.jain@sinaihealth.ca.
Mount Sinai Hospital · CAUniversity of Toronto · CAHospital for Sick Children · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInvestigate relevance of diastolic flow abnormalities in celiac trunk (aCT) and middle cerebral artery (aMCA) among preterms with persistent hemodynamically significant patent ductus arteriosus (phsPDA, diameter ≥ 1.5 mm, and age ≥ 7 days). STUDY

designFive hundred fifteen echocardiograms from 156 neonates born <28 weeks gestation age (GA) were analyzed retrospectively. Infants with aCT or aMCA at any time were compared with the rest. Separate comparisons were performed for aCT and aMCA. Primary outcome was composite of death, chronic lung disease (CLD), or necrotizing enterocolitis ≥ stage 2. Logistic regression was used to adjust for confounders.

resultMean (SD) weight and GA were 820(214) g and 25.2(1.3) weeks. aMCA, but not aCT, was associated with primary outcome [adjusted odds ratio 2.17, 95% CI: 1.01-4.67] and CLD [2.20 (0.99-4.87)].

conclusionaMCA may be a valid marker for defining the clinical significance of phsPDA in preterm neonates. aCeT may be of limited value in selecting patients for treatment.

Indexed as

Ductus Arteriosus, PatentEnterocolitis, NecrotizingPersistent Fetal Circulation SyndromeHumansInfant, Extremely PrematureInfant, NewbornRetrospective Studies

Identifiers

PMID32393829
OpenAlexW3022115429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.