Evidence map›Paper›PMID 32393583›Full record

ArticleeNeuro

Vitamin D Supplementation Rescues Aberrant NF-κB Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in

Mayara C Ribeiro, Seth M Moore, Noriyuki Kishi, Jeffrey D Macklis, Jessica L MacDonald

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. The Role of Vitamin D and Vitamin D Receptor in Sepsis.Current issues in molecular biology · 2025
    Review
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  5. Review
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mayara C RibeiroDepartment of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244.
Seth M MooreDepartment of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244.
Noriyuki KishiDepartment of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138.
Jeffrey D MacklisDepartment of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138 jemacdon@syr.edu jeffrey_macklis@harvard.edu.ORCID 0000-0003-3662-9698
Jessica L MacDonaldDepartment of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244 jemacdon@syr.edu jeffrey_macklis@harvard.edu.ORCID 0000-0002-9111-5756
Harvard University Press · USSyracuse University · US

Funding

Subcellular RNA-Proteome Mapping in Subtype- and Circuit-Specific Growth Cones: Development, Cell Biology, Disease, and RegenerationDP1NS106665 · NINDS · HARVARD UNIVERSITY · PI MACKLIS, JEFFREY D · 2017 to 2021
$5.9M
Molecular Development and Diversity of Callosal Projection NeuronsR01NS104055 · NINDS · HARVARD UNIVERSITY · PI MACKLIS, JEFFREY D · 2020 to 2024
$1.9M
Restoration of Homeostasis of Downstream Targets of MeCP2 as a Potential Therapeutic Avenue for Rett SyndromeR01NS106285 · NINDS · SYRACUSE UNIVERSITY · PI MACDONALD, JESSICA L. · 2019 to 2023
$1.6M
NINDS NIH HHS DP1 NS106665NINDS NIH HHS R01 NS104055NINDS NIH HHS R01 NS106285
6 · The paper itself

Abstract

Rett syndrome (RTT) is a severe, progressive X-linked neurodevelopmental disorder caused by mutations in the transcriptional regulator

Indexed as

Rett SyndromeAnimalsDietary SupplementsDisease Models, AnimalFemaleHumansMaleMethyl-CpG-Binding Protein 2MiceMice, Inbred C57BLMice, KnockoutNF-kappa BPhenotypeVitamin DMecp2 protein, mouseMethyl-CpG-Binding Protein 2NF-kappa BVitamin Depigeneticsneocortexneuronal morphologyNF-κBRett syndromevitamin D

Identifiers

PMID32393583
PMCPMC7253640
OpenAlexW3025168608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.